Personal profile
Research interests
Dr. Fehniger is interested in understanding innate immunity and its relationship to cancer. He focuses on the molecular and cellular biology of one innate immune lymphocyte, the natural killer cell, and developing translational immunotherapy strategies that utilize natural killer cells to fight cancer.
Clinical interests
Lymphoma, cellular therapy and bone marrow transplantation
Available to Mentor:
- PhD Students
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Collaborations and top research areas from the last five years
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A new immunotherapy ROR: Proximal ROR1 domain targeting breast cancer via monoclonal antibodies and CAR NK cells
Fehniger, T. A., Mar 4 2026, In: Molecular Therapy. 34, 3, p. 1304-1305 2 p.Research output: Contribution to journal › Comment/debate
Open Access -
A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma
Immune Atlas Consortium, Jan 2026, In: Nature Cancer. 7, 1, p. 224-246 23 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Exome sequencing of Hodgkin and non-Hodgkin composite lymphomas identifies shared somatic mutations indicative of common founding precursors
Gomez, F., Shea, L., Sharavanan, S. A., Russler-Germain, D., Mosior, M., Krysiak, K., Matlock, M., Skidmore, Z. L., Lee, Y.-S., Duncavage, E. J., O'Laughlin, M., Fronick, C., Fulton, R., Bartlett, N. L., Cashen, A. F., Griffith, M., Fehniger, T. A., Griffith, O. & Wartman, L. D., Jun 2026, In: Cancer Genetics. 304-305, p. 12-20 9 p.Research output: Contribution to journal › Article › peer-review
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ACLY promotes NK cell effector function by regulating glycolysis and histone acetylation
Sohn, H., Kolicheski, A., Poursine-Laurent, J., Tran, J., Wang, Y., Gan, K., Tobin, J. M., Saucier, N., Fehniger, T. A., Payton, J. E. & Cooper, M., Nov 1 2025, In: Journal of immunology (Baltimore, Md. : 1950). 214, 11, p. 3100-3114 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A Phase I Study of Romidepsin in Combination With Gemcitabine, Oxaliplatin, and Dexamethasone in Patients With Relapsed or Refractory Aggressive Lymphomas Enriched for T-Cell Lymphomas
Foley, N., Riedell, P. A., Bartlett, N. L., Cashen, A. F., Kahl, B. S., Fehniger, T. A., Fischer, A., Moreno, C., Liu, J., Carson, K. & Mehta-Shah, N., May 2025, In: Clinical Lymphoma, Myeloma and Leukemia. 25, 5, p. 328-336 9 p.Research output: Contribution to journal › Article › peer-review
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