Research output per year
Research output per year
Personal profile
Research interests
My recent research has focused on the integration and interpretation of diverse and heterogeneous pharmacogenomics data using statistical and machine learning approaches for i) understanding driver genetics/functional (mechanism), ii) discovering novel combinatory therapies to overcome intrinsic/acquired drug resistance (with reduced toxicity and synergy effects), and iii) uncovering and perturbing the tumor-stroma interaction to understand the roles of tumor micro-environment/niche in disease development.
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Research output
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Computational analysis to repurpose drugs for COVID-19 based on transcriptional response of host cells to SARS-CoV-2
Li, F., Michelson, A. P., Foraker, R., Zhan, M. & Payne, P. R. O., Dec 2021, In: BMC Medical Informatics and Decision Making. 21, 1, 15.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Investigating the relevance of major signaling pathways in cancer survival using a biologically meaningful deep learning model
Feng, J., Zhang, H. & Li, F., Dec 2021, In: BMC bioinformatics. 22, 1, 47.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Predicting mortality risk for preterm infants using random forest
Lee, J., Cai, J., Li, F. & Vesoulis, Z., Dec 2021, In: Scientific reports. 11, 1, 7308.Research output: Contribution to journal › Article › peer-review
Open Access -
Synergistic drug combination prediction by integrating multiomics data in deep learning models
Zhang, T., Zhang, L., Payne, P. R. O. & Li, F., 2021, Methods in Molecular Biology. Humana Press Inc., p. 223-238 16 p. (Methods in Molecular Biology; vol. 2194).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
1 Scopus citations -
Functional characterization of four ATP-binding cassette transporter A3 gene (ABCA3) variants
Hu, J. Y., Yang, P., Wegner, D. J., Heins, H. B., Luke, C. J., Li, F., White, F. V., Silverman, G. A., Sessions Cole, F. & Wambach, J. A., Jul 1 2020, In: Human mutation. 41, 7, p. 1298-1307 10 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations