Research Output per year
Research Output per year
Personal profile
Research interests
My recent research has focused on the integration and interpretation of diverse and heterogeneous pharmacogenomics data using statistical and machine learning approaches for i) understanding driver genetics/functional (mechanism), ii) discovering novel combinatory therapies to overcome intrinsic/acquired drug resistance (with reduced toxicity and synergy effects), and iii) uncovering and perturbing the tumor-stroma interaction to understand the roles of tumor micro-environment/niche in disease development.
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Research Output
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Synergistic drug combination prediction by integrating multiomics data in deep learning models
Zhang, T., Zhang, L., Payne, P. R. O. & Li, F., 2021, Methods in Molecular Biology. Humana Press Inc., p. 223-238 16 p. (Methods in Molecular Biology; vol. 2194).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Functional characterization of four ATP-binding cassette transporter A3 gene (ABCA3) variants
Hu, J. Y., Yang, P., Wegner, D. J., Heins, H. B., Luke, C. J., Li, F., White, F. V., Silverman, G. A., Sessions Cole, F. & Wambach, J. A., Jul 1 2020, In : Human mutation. 41, 7, p. 1298-1307 10 p.Research output: Contribution to journal › Article
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Integrative network analysis identifies potential targets and drugs for ovarian cancer
Zhang, T., Zhang, L. & Li, F., Sep 21 2020, In : BMC Medical Genomics. 13, 132.Research output: Contribution to journal › Article
Open Access1 Scopus citations -
Synergy from gene expression and network mining (SynGeNet) method predicts synergistic drug combinations for diverse melanoma genomic subtypes
Regan-Fendt, K. E., Xu, J., DiVincenzo, M., Duggan, M. C., Shakya, R., Na, R., Carson, W. E., Payne, P. R. O. & Li, F., Dec 1 2019, In : npj Systems Biology and Applications. 5, 1, 6.Research output: Contribution to journal › Article
Open Access11 Scopus citations -
Systematic identification of druggable epithelial-stromal crosstalk signaling networks in ovarian cancer
Yeung, T. L., Sheng, J., Leung, C. S., Li, F., Kim, J., Ho, S. Y., Matzuk, M. M., Lu, K. H., Wong, S. T. C. & Mok, S. C., Jan 1 2019, In : Journal of the National Cancer Institute. 111, 3, p. 272-282 11 p.Research output: Contribution to journal › Article
Open Access5 Scopus citations