Brian DeBosch

Assistant Professor of Pediatrics, Assistant Professor of Cell Biology and Physiology

    • 1098 Citations

    Research output per year

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    Personal profile

    Research interests

    Our group studies gut determinants of metabolic disease. Specifically, we focus on hepatic and intestinal sugar transporters in the glucose transporter (GLUT) family and the role they play in predisposing to or protecting from metabolic syndrome, type 2 diabetes mellitus and non-alcoholic fatty liver disease.

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    Research Output

    • 1098 Citations
    • 26 Article
    • 3 Review article
    • 1 Conference contribution

    Lactotrehalose, an Analog of Trehalose, Increases Energy Metabolism Without Promoting Clostridioides difficile Infection in Mice

    Zhang, Y., Shaikh, N., Ferey, J. L., Wankhade, U. D., Chintapalli, S. V., Higgins, C. B., Crowley, J. R., Heitmeier, M. R., Stothard, A. I., Mihi, B., Good, M., Higashiyama, T., Swarts, B. M., Hruz, P. W., Shankar, K., Tarr, P. I. & DeBosch, B. J., Apr 2020, In : Gastroenterology. 158, 5, p. 1402-1416.e2

    Research output: Contribution to journalArticle

  • 2 Scopus citations

    Microbial and metabolic impacts of trehalose and trehalose analogues

    Zhang, Y. & DeBosch, B. J., Sep 2 2020, In : Gut microbes. 11, 5, p. 1475-1482 8 p.

    Research output: Contribution to journalArticle

    Open Access
  • Targeting hepatocyte carbohydrate transport to mimic fasting and calorie restriction

    Kading, J., Finck, B. N. & DeBosch, B. J., 2020, (Accepted/In press) In : FEBS Journal.

    Research output: Contribution to journalReview article

    Open Access
  • A maternal high-fat, high-sucrose diet induces transgenerational cardiac mitochondrial dysfunction independently of maternal mitochondrial inheritance

    Ferey, J. L. A., Boudoures, A. L., Reid, M., Drury, A., Scheaffer, S., Modi, Z., Kovacs, A., Pietka, T., DeBosch, B. J., Thompson, M. D., Diwan, A. & Moley, K. H., May 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 316, 5, p. H1202-H1210

    Research output: Contribution to journalArticle

  • 10 Scopus citations

    Breath Collection from Children for Disease Biomarker Discovery

    Berna, A. Z., DeBosch, B., Stoll, J. & Odom John, A. R., Feb 14 2019, In : Journal of visualized experiments : JoVE. 144

    Research output: Contribution to journalArticle