Azaanthraquinone: An antimicrobial alkaloid from Mitracarpus scaber

Adewole L. Okunade, Alice M. Clark, Charles D. Hufford, Babajide O. Oguntimein

Research output: Contribution to journalArticlepeer-review

47 Scopus citations

Abstract

An ethanolic extract of the aerial parts of Mitracarpus scaber demonstrated good antimicrobial activity. Bioassay directed fractionation of this extract led to the isolation of benz[g]isoquinoline-5,10-dione (1) as an active component. Compound 1 showed significant in vitro inhibitory activity against the AIDS-related pathogens.

Original languageEnglish
Pages (from-to)447-448
Number of pages2
JournalPlanta Medica
Volume65
Issue number5
DOIs
StatePublished - 1999

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