Zoonotic Bacterial Infections Triggering Cytokine Storm Syndrome

Zaher K. Otrock, Charles S. Eby

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Zoonotic infections can result in life-threatening complications that can manifest with hemophagocytic lymphohistiocytosis (HLH)/cytokine storm syndrome (CSS). Bacteria constitute the largest group of zoonotic infection-related HLH cases. The growing list of zoonotic bacterial infections associated with HLH/CSS include Brucella spp., Rickettsia spp., Ehrlichia, Coxiella burnetii, Mycobacterium spp., and Bartonella spp. Patients most commonly present with fever, cytopenias, hepatosplenomegaly, myalgias, and less frequently with rash, jaundice, and lymphadenopathy.

Original languageEnglish
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer
Pages285-291
Number of pages7
DOIs
StatePublished - 2024

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1448
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

Keywords

  • Bacteria
  • Bartonella
  • Brucella
  • Case reports
  • Cytokine storm syndrome
  • Ehrlichia
  • Hemophagocytic lymphohistiocytosis
  • Review
  • Rickettsia
  • Trigger
  • Zoonotic

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