TY - JOUR
T1 - Zika Virus Infection in Children
AU - Hendrixson, David Taylor
AU - Newland, Jason G.
N1 - Publisher Copyright:
© 2017 Elsevier Inc.
PY - 2018/3
Y1 - 2018/3
N2 - Zika virus is a mosquito-borne Flavivirus responsible for symptomatic and asymptomatic infections in humans. Zika was first identified in Africa as a cause of sporadic febrile illness. Beginning in 2015, Zika virus infection was identified in Brazil and linked with several symptomatic infections. Notably, congenital infections were observed with marked neurologic abnormalities. Diagnosis relies on detection of Zika virus by real-time polymerase chain reaction or by the presence of anti-Zika antibodies. Treatment of this viral illness remains supportive; however, proactive screening and interventions are indicated in the treatment of infants with symptomatic congenital infection.
AB - Zika virus is a mosquito-borne Flavivirus responsible for symptomatic and asymptomatic infections in humans. Zika was first identified in Africa as a cause of sporadic febrile illness. Beginning in 2015, Zika virus infection was identified in Brazil and linked with several symptomatic infections. Notably, congenital infections were observed with marked neurologic abnormalities. Diagnosis relies on detection of Zika virus by real-time polymerase chain reaction or by the presence of anti-Zika antibodies. Treatment of this viral illness remains supportive; however, proactive screening and interventions are indicated in the treatment of infants with symptomatic congenital infection.
KW - Arthropod-borne disease
KW - Congenital infection
KW - Flavivirus
KW - Microcephaly
KW - Vertical transmission
KW - Zika virus
UR - http://www.scopus.com/inward/record.url?scp=85041348186&partnerID=8YFLogxK
U2 - 10.1016/j.idc.2017.10.003
DO - 10.1016/j.idc.2017.10.003
M3 - Review article
C2 - 29406975
AN - SCOPUS:85041348186
SN - 0891-5520
VL - 32
SP - 215
EP - 224
JO - Infectious disease clinics of North America
JF - Infectious disease clinics of North America
IS - 1
ER -