Zebrafish melanoma

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

3 Scopus citations

Abstract

Melanoma skin cancer is a potentially deadly disease in humans and has remained extremely difficult to treat once it has metastasized. In just the last 10 years, a number of models of melanoma have been developed in the zebrafish that are biologically faithful to the human disease and have already yielded important insights into the fundamental biology of melanoma and offered new potential avenues for treatment. With the diversity and breadth of the molecular genetic tools available in the zebrafish, these melanoma models will continue to be refined and expanded upon to keep pace with the rapidly evolving field of melanoma biology.

Original languageEnglish
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Pages439-450
Number of pages12
DOIs
StatePublished - 2016

Publication series

NameAdvances in Experimental Medicine and Biology
Volume916
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

Keywords

  • Cancer models
  • Drug discovery
  • Melanoma
  • Transgenics
  • Zebrafish

Fingerprint

Dive into the research topics of 'Zebrafish melanoma'. Together they form a unique fingerprint.

Cite this