Zbrowse: An interactive GWAS results browser

Greg R. Ziegler; Ryan H. Hartsock; Ivan Baxter

doi:10.7717/peerj-cs.3

Zbrowse: An interactive GWAS results browser

Greg R. Ziegler, Ryan H. Hartsock, Ivan Baxter

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

The growing number of genotyped populations, the advent of high-throughput phenotyping techniques and the development ofGWAS analysis software has rapidly accelerated the number of GWAS experimental results. Candidate gene discovery from these results files is often tedious, involving many manual steps searching for genes in windows around a significant SNP. This problem rapidly becomes more complex when an analyst wishes to compare multiple GWAS studies for pleiotropic or environment specific effects. To this end, we have developed a fast and intuitive interactive browser for the viewing of GWAS results with a focus on an ability to compare results across multiple traits or experiments. The software can easily be run on a desktop computer with software that bioinformaticians are likely already familiar with. Additionally, the software can be hosted or embedded on a server for easy access by anyone with a modern web browser.

Original language	English
Article number	e3
Journal	PeerJ Computer Science
Volume	2015
Issue number	5
DOIs	https://doi.org/10.7717/peerj-cs.3
State	Published - 2015

Keywords

Association mapping
Data visualization
GWAS

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10.7717/peerj-cs.3

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abstract = "The growing number of genotyped populations, the advent of high-throughput phenotyping techniques and the development ofGWAS analysis software has rapidly accelerated the number of GWAS experimental results. Candidate gene discovery from these results files is often tedious, involving many manual steps searching for genes in windows around a significant SNP. This problem rapidly becomes more complex when an analyst wishes to compare multiple GWAS studies for pleiotropic or environment specific effects. To this end, we have developed a fast and intuitive interactive browser for the viewing of GWAS results with a focus on an ability to compare results across multiple traits or experiments. The software can easily be run on a desktop computer with software that bioinformaticians are likely already familiar with. Additionally, the software can be hosted or embedded on a server for easy access by anyone with a modern web browser.",

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Zbrowse: An interactive GWAS results browser

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Keywords

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