WormBase: A modern Model Organism Information Resource

Todd W. Harris, Valerio Arnaboldi, Scott Cain, Juancarlos Chan, Wen J. Chen, Jaehyoung Cho, Paul Davis, Sibyl Gao, Christian A. Grove, Ranjana Kishore, Raymond Y.N. Lee, Hans Michael Muller, Cecilia Nakamura, Paulo Nuin, Michael Paulini, Daniela Raciti, Faye H. Rodgers, Matthew Russell, Gary Schindelman, Kimberly V. AukenQinghua Wang, Gary Williams, Adam J. Wright, Karen Yook, Kevin L. Howe, Tim Schedl, Lincoln Stein, Paul W. Sternberg

Research output: Contribution to journalArticlepeer-review

107 Scopus citations

Abstract

WormBase (https://wormbase.org/) is a mature Model Organism Information Resource supporting researchers using the nematode Caenorhabditis elegans as a model system for studies across a broad range of basic biological processes. Toward this mission, WormBase efforts are arranged in three primary facets: curation, user interface and architecture. In this update, we describe progress in each of these three areas. In particular, we discuss the status of literature curation and recently added data, detail new features of the web interface and options for users wishing to conduct data mining workflows, and discuss our efforts to build a robust and scalable architecture by leveraging commercial cloud offerings. We conclude with a description of WormBase's role as a founding member of the nascent Alliance of Genome Resources.

Original languageEnglish
Pages (from-to)D762-D767
JournalNucleic acids research
Volume48
Issue numberD1
DOIs
StatePublished - Jan 1 2020

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