Withdrawal of luteal phase support in the management of ectopic pregnancy following frozen embryo transfer a case report

Hannah M. Ware, Vinita M. Alexander, Valerie S. Ratts

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND: Management of ectopic pregnancy includes expectant, medical, or surgical approaches. Assisted reproductive technology (ART) is a risk fac-tor for ectopic pregnancy. Expectant management is less well studied in patients utilizing ART with frozen embryo transfer (FET). CASE: After undergoing FET, a 50-year-old woman developed a tubal ectopic pregnancy. Hormonal support of the luteal phase was stopped. Serial β-hCG mea-surement and transvaginal ultrasounds documented res-olution. CONCLUSION: This is one of the first case reports describing withdrawal of hormonal support as successful management of ectopic pregnancy following FET. In selected cases, this management strategy may help patients avoid side effects of methotrexate and surgery and, in patients seeking conception via ART, may pre-vent delays until the next ART cycles. (J Reprod Med 2020;65:311–314).

Original languageEnglish
Pages (from-to)311-314
Number of pages4
JournalJournal of Reproductive Medicine
Volume65
Issue number5
StatePublished - Oct 2020

Keywords

  • Abortifacient agents
  • Abortion, spon-taneous
  • Assisted reproductive technology
  • Chori-onic gonadotropin
  • Diagnosis, differential
  • Embryo transfer
  • Fertilization
  • Lu-teal phase
  • Methotrexate
  • Pregnancy, ectopic
  • Ul-trasonography
  • Watchful waiting

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