Why We Should Put Clothes on Mice

Irfan J. Lodhi; Clay F. Semenkovich

doi:10.1016/j.cmet.2009.01.004

Why We Should Put Clothes on Mice

Irfan J. Lodhi, Clay F. Semenkovich

Research output: Contribution to journal › Short survey › peer-review

80 Scopus citations

Abstract

Mitochondrial uncoupling protein 1 (UCP1) is a key regulator of adaptive thermogenesis and energy expenditure. Mice lacking UCP1 are cold sensitive, but surprisingly not obese at room temperature. In this issue of Cell Metabolism, Feldmann et al. (2009) unmask an obesogenic phenotype by simply maintaining these mice at thermoneutrality.

Original language	English
Pages (from-to)	111-112
Number of pages	2
Journal	Cell metabolism
Volume	9
Issue number	2
DOIs	https://doi.org/10.1016/j.cmet.2009.01.004
State	Published - Feb 4 2009

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title = "Why We Should Put Clothes on Mice",

abstract = "Mitochondrial uncoupling protein 1 (UCP1) is a key regulator of adaptive thermogenesis and energy expenditure. Mice lacking UCP1 are cold sensitive, but surprisingly not obese at room temperature. In this issue of Cell Metabolism, Feldmann et al. (2009) unmask an obesogenic phenotype by simply maintaining these mice at thermoneutrality.",

author = "Lodhi, {Irfan J.} and Semenkovich, {Clay F.}",

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AU - Semenkovich, Clay F.

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AB - Mitochondrial uncoupling protein 1 (UCP1) is a key regulator of adaptive thermogenesis and energy expenditure. Mice lacking UCP1 are cold sensitive, but surprisingly not obese at room temperature. In this issue of Cell Metabolism, Feldmann et al. (2009) unmask an obesogenic phenotype by simply maintaining these mice at thermoneutrality.

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M3 - Short survey

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SN - 1550-4131

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SP - 111

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JO - Cell metabolism

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Why We Should Put Clothes on Mice

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