Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

Keyphrases

• Alzheimer's Disease 100%
• Whole Exome Sequencing 100%
• Transcriptional Regulation 100%
• Sequencing Studies 100%
• Immune Regulation 100%
• Alzheimer 100%
• European Ancestry 66%
• Caribbean Hispanics 66%
• Alzheimer's Disease Sequencing Project 66%
• Non-coding RNA (ncRNA) 33%
• Disease Case 33%
• Gain-of-function mutation 33%
• Late-onset Alzheimer's Disease 33%
• Family History 33%
• Alzheimer's Disease Risk 33%
• Alzheimer's Disease Pathology 33%
• Zinc Finger Protein 33%
• Risk Variant 33%
• Family-centered 33%
• Cognitively Normal 33%
• Novel Genes 33%
• Whole Genome 33%
• Multiple Variants 33%
• Risk Score 33%
• Single nucleotide Variant 33%
• Multiple Models 33%
• Gene-based 33%
• Immunoglobulin Genes 33%
• Genome-wide Genotyping 33%
• Gene Testing 33%
• Risk Control 33%
• Functional Genetic Variants 33%
• Insertion Polymorphism 33%
• Multiple Testing Correction 33%
• Hispanic Families 33%
• ZNF655 33%

Biochemistry, Genetics and Molecular Biology

• Exome Sequencing 100%
• Immune Response 100%
• Long Non-Coding RNA 33%
• Single-Nucleotide Polymorphism 33%
• Genetic Divergence 33%
• Genotyping 33%
• Indel 33%
• Haplotype 33%
• Immunoglobulin Gene 33%
• Amyloid Protein 33%