Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol

Keyphrases

• Whole Exome Sequencing 100%
• Low-density Lipoprotein Cholesterol (LDL-C) 100%
• Coding Variants 100%
• LDL Cholesterol 100%
• Frequency Coding 100%
• Genome-wide Association Study 33%
• Sequencing Studies 33%
• Low-frequency Variants 33%
• PNPLA5 33%
• Associated Genes 16%
• Low-density Lipoprotein Receptor 16%
• Genotype 16%
• Risk Factors for Cardiovascular Diseases 16%
• SNP 16%
• Rare Variants 16%
• Exome 16%
• Large-scale Sequencing 16%
• Phospholipase 16%
• Lipid Levels 16%
• Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) 16%
• Similarity Experiment 16%
• Heritable Risk 16%
• Lipid Metabolism Genes 16%

Biochemistry, Genetics and Molecular Biology

• Exome Sequencing 100%
• Low-Density Lipoprotein 100%
• Genome-Wide Association Study 33%
• Exome 16%
• Lipid 16%
• Single Nucleotide Polymorphism 16%
• Phospholipase 16%
• Genotyping 16%
• Lipid Level 16%
• PCSK9 16%
• Rare Variant 16%