When T cells run out of breath: The HIF-1α story

Katherine Nutsch, Chyi Hsieh

Research output: Contribution to journalShort survey

7 Scopus citations

Abstract

In this issue, Dang et al. (2011) report a role for the hypoxia-induced transcription factor HIF-1α in regulating the differentiation of T cell subsets that impact both inflammation and its resolution. Their findings illustrate how metabolic signals can alter the balance between inflammation and tolerance and present a potential therapeutic opportunity for the treatment of diseases associated with chronic inflammation.

Original languageEnglish
Pages (from-to)673-674
Number of pages2
JournalCell
Volume146
Issue number5
DOIs
StatePublished - Sep 2 2011

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