What do you need to know about traditional insulin formulations?

Research output: Contribution to journalReview articlepeer-review


Although insulin analogues show noninferiority to conventional insulins in regard to glycemic control and hemoglobin A1c reductions3 they are significantly more expensive, and health care providers need to better understand how to transition some patients back to more affordable options. Newer long-acting and ultra-long-acting insulins allow for more flexibility in timing of insulin administration compared with the traditional NPH basal insulin. The newer ultra-long-acting basal options even have a lower risk of hypoglycemia compared with the newer long-acting insulins.3 Changing to more-traditional forms of basal insulins would therefore require close attention and adjustments to provide a reasonable margin of glycemic safety.

Original languageEnglish
Pages (from-to)14-17
Number of pages4
Issue number11
StatePublished - Nov 2020


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