WE‐E‐ValA‐06: A Real‐Time MRI Guided External Beam Radiotherapy Delivery System

J. Dempsey, B. Dionne, J. Fitzsimmons, A. Haghigat, J. li, D. Low, S. Mutic, J. Palta, H. Romeijn, G. Sjoden

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

Purpose: We present feasibility studies in support of a real‐time MRI guided external beam radiotherapy delivery system currently under commercial development. Method and Materials: The system, (ViewRay Inc., Renaissance™), combines a low field open MRI scanner and a multi‐headed 60Co γ‐ray IMRT unit equipped with multi‐leaf collimators. It is designed so that the center of the field of view of the MRI and the isocenter of the radiotherapy unit coincide. The inherent compatibility of the units allows for the acquisition of fast ciné MRI simultaneous to radiotherapy delivery to assess intra‐fraction organ motion. Computational feasibility studies were performed to investigate: the compatibility of the MRI and the 60Co γ‐ray IMRT unit; the impact of the MRI magnetic field on the dosimetry; and the feasibility of performing accurate heterogeneity dose computations with MRI data. Results: The 60Co γ‐ray IMRT unit was found not to significantly impact the operation of the MRI; the γ‐ray IMRT unit is capable of producing high quality IMRT treatment plans; the MRI magnetic field eliminates contamination electrons and does not significantly perturb the dose distribution in lung, soft tissue, and bone; and accurate heterogeneity dose computations are possible employing only MRI data. Conclusion: Performing IMRT allows for the seamless integration with, and simultaneous operation of, an open MRI unit. Conflict of Interest: Research sponsored by ViewRay, Inc., Gainesville, Florida USA.

Original languageEnglish
Number of pages1
JournalMedical physics
Volume33
Issue number6
DOIs
StatePublished - Jun 2006

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    Dempsey, J., Dionne, B., Fitzsimmons, J., Haghigat, A., li, J., Low, D., Mutic, S., Palta, J., Romeijn, H., & Sjoden, G. (2006). WE‐E‐ValA‐06: A Real‐Time MRI Guided External Beam Radiotherapy Delivery System. Medical physics, 33(6). https://doi.org/10.1118/1.2241803