TY - JOUR
T1 - Weaving New Insights for the Genetic Regulation of Human Cognitive Phenotypes
AU - Mulvey, Bernard
AU - Dougherty, Joseph D.
N1 - Publisher Copyright:
© 2017 Elsevier Inc.
PY - 2018/1/11
Y1 - 2018/1/11
N2 - Psychiatric genetic studies have drawn associations between human cognitive traits and noncoding genomic variants. However, the mechanistic effects of these variants are unclear. By weaving in strands of genomic data from developing human brains, de la Torre-Ubieta et al. tie disease-associated loci to functional enhancers, target genes, and putatively affected cell types. Psychiatric genetic studies have drawn associations between human cognitive traits and noncoding genomic variants. However, the mechanistic effects of these variants are unclear. By weaving in strands of genomic data from developing human brains, de la Torre-Ubieta et al. tie disease-associated loci to functional enhancers, target genes, and putatively affected cell types.
AB - Psychiatric genetic studies have drawn associations between human cognitive traits and noncoding genomic variants. However, the mechanistic effects of these variants are unclear. By weaving in strands of genomic data from developing human brains, de la Torre-Ubieta et al. tie disease-associated loci to functional enhancers, target genes, and putatively affected cell types. Psychiatric genetic studies have drawn associations between human cognitive traits and noncoding genomic variants. However, the mechanistic effects of these variants are unclear. By weaving in strands of genomic data from developing human brains, de la Torre-Ubieta et al. tie disease-associated loci to functional enhancers, target genes, and putatively affected cell types.
UR - http://www.scopus.com/inward/record.url?scp=85041113932&partnerID=8YFLogxK
U2 - 10.1016/j.cell.2017.12.037
DO - 10.1016/j.cell.2017.12.037
M3 - Short survey
C2 - 29328907
AN - SCOPUS:85041113932
SN - 0092-8674
VL - 172
SP - 10
EP - 13
JO - Cell
JF - Cell
IS - 1-2
ER -