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WDFY4-dependent cross-presentation proceeds via a vacuolar antigen-processing route
J. Luke Postoak
, Alyssa Koch
, Sicong Shan
, Ray A. Ohara
, Suin Jo
, Jing Chen
, Pritesh Desai
, Feiya Ou
, Magdalena Kraft
,
Michael S. Diamond
, Sunkyung Kim
,
Theresa L. Murphy
,
Kenneth M. Murphy
Division of Infectious Diseases
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
DBBS - Immunology
DBBS - Molecular Microbiology and Microbial Pathogenesis
Institute of Clinical and Translational Sciences (ICTS)
Brain Tumor Center
Bursky Center for Human Immunology & Immunotherapy Programs (CHiiPs)
Rheumatic Diseases Research Resource-Based Center
COVID-19 Researchers
Division of Immunobiology
Siteman Cancer Center
DBBS - Developmental, Regenerative and Stem Cell Biology
DBBS - Molecular Cell Biology
Research output
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Keyphrases
Antigen Processing
100%
Processing Route
100%
Cross-presentation
100%
WDFY4
100%
MHC Class I Molecules
60%
CDC1
60%
Endoplasmic Reticulum
40%
Peptide-loading Complex
40%
Dendritic Cells
20%
Viral
20%
Golgi Compartment
20%
Proteasomal Degradation
20%
Tumor Antigen
20%
Phagolysosome
20%
Intracellular Processing
20%
Endocytic Compartment
20%
Peptide Transport
20%
Immunology and Microbiology
Antigen Presentation
100%
Cross-Presentation
100%
Peptides
80%
MHC Class I
60%
Endoplasmic reticulum
40%
Dendritic Cell
20%
Cytosol
20%
Tumor Antigen
20%
Phagolysosome
20%