Volumetric diffuse optical tomography of brain activity

Joseph P. Culver; Andrew M. Siegel; Jonathan J. Stott; David A. Boas

doi:10.1364/OL.28.002061

Volumetric diffuse optical tomography of brain activity

Joseph P. Culver, Andrew M. Siegel, Jonathan J. Stott, David A. Boas

Research output: Contribution to journal › Article › peer-review

152 Scopus citations

Abstract

We present three-dimensional diffuse optical tomography of the hemodynamic response to somatosensory stimulation in a rat. These images show the feasibility of volumetrically imaging the functional response to brain activity with diffuse light. A combination of positional optode calibration and contrast-to-noise ratio weighting was found to improve imaging performance.

Original language	English
Pages (from-to)	2061-2063
Number of pages	3
Journal	Optics Letters
Volume	28
Issue number	21
DOIs	https://doi.org/10.1364/OL.28.002061
State	Published - Nov 1 2003

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10.1364/OL.28.002061

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title = "Volumetric diffuse optical tomography of brain activity",

abstract = "We present three-dimensional diffuse optical tomography of the hemodynamic response to somatosensory stimulation in a rat. These images show the feasibility of volumetrically imaging the functional response to brain activity with diffuse light. A combination of positional optode calibration and contrast-to-noise ratio weighting was found to improve imaging performance.",

author = "Culver, {Joseph P.} and Siegel, {Andrew M.} and Stott, {Jonathan J.} and Boas, {David A.}",

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AU - Culver, Joseph P.

AU - Siegel, Andrew M.

AU - Stott, Jonathan J.

AU - Boas, David A.

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AB - We present three-dimensional diffuse optical tomography of the hemodynamic response to somatosensory stimulation in a rat. These images show the feasibility of volumetrically imaging the functional response to brain activity with diffuse light. A combination of positional optode calibration and contrast-to-noise ratio weighting was found to improve imaging performance.

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SN - 0146-9592

VL - 28

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EP - 2063

JO - Optics Letters

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IS - 21

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Volumetric diffuse optical tomography of brain activity

Abstract

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