Vitamin D and Bone Health Among Children With Epilepsy

Renée A. Shellhaas, Sucheta M. Joshi

Research output: Contribution to journalReview articlepeer-review

54 Scopus citations


The lay media and scientific literature have focused increasing attention on vitamin D deficiency and insufficiency in recent years. Low vitamin D levels confer increased an risk of abnormal bone mineralization, and are linked to poor bone health in epilepsy patients. However, vitamin D is not the only determinant of bone health in children with epilepsy. Anticonvulsant medications, in addition to features and comorbidities of epilepsy and coexisting neurologic diseases, are important factors in this complex topic. We review the basic metabolism of vitamin D in terms of bone health among children with epilepsy. We also discuss the literature regarding vitamin D and bone mineral density in this population. Finally, we suggest algorithms for screening and treating vitamin D insufficiency in these patients.

Original languageEnglish
Pages (from-to)385-393
Number of pages9
JournalPediatric Neurology
Issue number6
StatePublished - Jun 2010


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