Visualizing Mitochondrial Lipids and Fusion Events in Mammalian Cells

Huiyan Huang, Michael A. Frohman

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Scopus citations

Abstract

Mitochondria are dynamic organelles that frequently undergo fusion and fission, the balance of which is critical for proper cellular functioning and viability. Most studies on mitochondrial fusion and fission mechanisms have focused on proteins thought to physically mediate the events. However, dynamic changes in membrane phospholipids also play roles in facilitating the fusion and fission events. This chapter will review the importance of lipids in mitochondrial dynamics and some of the methods that can be used to study the function of lipids in mitochondrial fusion and fission.

Original languageEnglish
Title of host publicationMethods in Cell Biology
PublisherAcademic Press Inc.
Pages131-145
Number of pages15
DOIs
StatePublished - 2012
Externally publishedYes

Publication series

NameMethods in Cell Biology
Volume108
ISSN (Print)0091-679X

Keywords

  • Cellular functioning
  • Dynamic organelle
  • Fission
  • Fusion
  • Mitochondria
  • Phospholipid

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  • Cite this

    Huang, H., & Frohman, M. A. (2012). Visualizing Mitochondrial Lipids and Fusion Events in Mammalian Cells. In Methods in Cell Biology (pp. 131-145). (Methods in Cell Biology; Vol. 108). Academic Press Inc.. https://doi.org/10.1016/B978-0-12-386487-1.00007-9