TY - JOUR
T1 - Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
AU - Rajamani, Karthikeyan D.
AU - Sambandam, Sankar
AU - Mukhopadhyay, Krishnendu
AU - Puttaswamy, Naveen
AU - Thangavel, Gurusamy
AU - Natesan, Durairaj
AU - Ramasamy, Rengaraj
AU - Sendhil, Saritha
AU - Natarajan, Amudha
AU - Aravindalochan, Vigneswari
AU - Pillarisetti, Ajay
AU - Johnson, Michael
AU - Rosenthal, Joshua
AU - Steenland, Kyle
AU - Piedhrahita, Ricardo
AU - Peel, Jennifer
AU - Clark, Maggie L.
AU - Barr, Dana Boyd
AU - Rajkumar, Sarah
AU - Young, Bonnie
AU - Jabbarzadeh, Shirin
AU - Rosa, Ghislaine
AU - Kirby, Miles
AU - Underhill, Lindsay J.
AU - Diaz-Artiga, Anaite
AU - Lovvorn, Amy
AU - Checkley, William
AU - Clasen, Thomas
AU - Balakrishnan, Kalpana
N1 - Funding Information:
This study was funded by the U.S. National Institutes of Health (cooperative agreement 1UM1HL134590) in collaboration with the Bill & Melinda Gates Foundation (OPP1131279). A multidisciplinary, independent Data and Safety Monitoring Board (DSMB) appointed by the National Heart, Lung, and Blood Institute (NHLBI) monitors the quality of the data and protects the safety of patients enrolled in the HAPIN trial. NHLBI DSMB: Nancy R. Cook, Stephen Hecht, Catherine Karr (Chair), Joseph Millum, Nalini Sathiakumar, Paul K. Whelton, Gail Weinmann and Thomas Croxton (Executive Secretaries). Program Coordination: Gail Rodgers, Bill & Melinda Gates Foundation; Claudia L. Thompson, National Institute of Environmental Health Science; Mark J. Parascandola, National Cancer Institute; Marion Koso-Thomas, Eunice Kennedy Shriver National Institute of Child Health and Human Development; Joshua P. Rosenthal, Fogarty International Center; Conception R. Nierras, NIH Office of Strategic Coordination Common Fund; Katherine Kavounis, Dong-Yun Kim, Antonello Punturieri, and Barry S. Schmetter, NHLBI.
Publisher Copyright:
© 2022 JoVE Journal of Visualized Experiments.
PY - 2022/12
Y1 - 2022/12
N2 - Here, we present a visual representation of standard procedures to collect population-level data on personal exposures to household air pollution (HAP) from two different study sites in a resource-constrained setting of Tamil Nadu, India. Particulate matter PM2.5 (particles smaller than 2.5 microns in aerodynamic diameter), carbon monoxide (CO), and black carbon (BC) were measured in pregnant mothers (M), other adult women (OAW), and children (C) at various times over a 4 year period. In addition, stove usage monitoring (SUMs) with data-logging thermometers and ambient measurements of air pollution were carried out. Furthermore, the feasibility of collecting biological samples (urine and dried blood spots [DBSs]) from study participants at the field sites was successfully demonstrated. Based on findings from this and earlier studies, the methods used here have enhanced the data quality and avoided issues with household air pollution and biological sample collection in resource-constrained situations. The procedures established may be a valuable educational tool and resource for researchers conducting similar air pollution and health studies in India and other low-and middle-income countries (LMICs).
AB - Here, we present a visual representation of standard procedures to collect population-level data on personal exposures to household air pollution (HAP) from two different study sites in a resource-constrained setting of Tamil Nadu, India. Particulate matter PM2.5 (particles smaller than 2.5 microns in aerodynamic diameter), carbon monoxide (CO), and black carbon (BC) were measured in pregnant mothers (M), other adult women (OAW), and children (C) at various times over a 4 year period. In addition, stove usage monitoring (SUMs) with data-logging thermometers and ambient measurements of air pollution were carried out. Furthermore, the feasibility of collecting biological samples (urine and dried blood spots [DBSs]) from study participants at the field sites was successfully demonstrated. Based on findings from this and earlier studies, the methods used here have enhanced the data quality and avoided issues with household air pollution and biological sample collection in resource-constrained situations. The procedures established may be a valuable educational tool and resource for researchers conducting similar air pollution and health studies in India and other low-and middle-income countries (LMICs).
UR - http://www.scopus.com/inward/record.url?scp=85145338534&partnerID=8YFLogxK
U2 - 10.3791/64144
DO - 10.3791/64144
M3 - Article
C2 - 36622010
AN - SCOPUS:85145338534
SN - 1940-087X
VL - 2022
JO - Journal of visualized experiments : JoVE
JF - Journal of visualized experiments : JoVE
IS - 190
M1 - e64144
ER -