TY - JOUR
T1 - Virome genomics
T2 - A tool for defining the human virome
AU - Wylie, Kristine M.
AU - Weinstock, George M.
AU - Storch, Gregory A.
PY - 2013/8
Y1 - 2013/8
N2 - High throughput, deep sequencing assays are powerful tools for gaining insights into virus-host interactions. Sequencing assays can discover novel viruses and describe the genomes of novel and known viruses. Genomic information can predict viral proteins that can be characterized, describe important genes in the host that control infections, and evaluate gene expression of viruses and hosts during infection. Sequencing can also describe variation and evolution of viruses during replication and transmission. This review recounts some of the major advances in the studies of virus-host interactions from the last two years, and discusses the uses of sequencing technologies relating to these studies.
AB - High throughput, deep sequencing assays are powerful tools for gaining insights into virus-host interactions. Sequencing assays can discover novel viruses and describe the genomes of novel and known viruses. Genomic information can predict viral proteins that can be characterized, describe important genes in the host that control infections, and evaluate gene expression of viruses and hosts during infection. Sequencing can also describe variation and evolution of viruses during replication and transmission. This review recounts some of the major advances in the studies of virus-host interactions from the last two years, and discusses the uses of sequencing technologies relating to these studies.
UR - http://www.scopus.com/inward/record.url?scp=84882824861&partnerID=8YFLogxK
U2 - 10.1016/j.mib.2013.04.006
DO - 10.1016/j.mib.2013.04.006
M3 - Review article
C2 - 23706900
AN - SCOPUS:84882824861
SN - 1369-5274
VL - 16
SP - 479
EP - 484
JO - Current Opinion in Microbiology
JF - Current Opinion in Microbiology
IS - 4
ER -