Abstract
Clostridium difficile infections in children are increasing. In this cohort study, we enrolled 62 children with diarrhea and C difficile. We performed polymerase chain reaction assays to detect viral agents of gastroenteritis and quantify C difficile burden. Fifteen (24%) children diagnosed as having C difficile infection had a concomitant viral co-infection. These patients tended to be younger and had a higher C difficile bacterial burden than children with no viral co-infections (median difference =  565,957 cfu/mL; P =  0.011), but were clinically indistinguishable. The contribution of viral co-infection to C difficile disease in children warrants future investigation.
Original language | English |
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Pages (from-to) | 813-816 |
Number of pages | 4 |
Journal | Journal of pediatric gastroenterology and nutrition |
Volume | 57 |
Issue number | 6 |
DOIs | |
State | Published - Dec 2013 |
Keywords
- C difficile
- Children
- Norovirus
- Viral gastroenteritis