Vessel segmentation analysis of ischemic stroke images acquired with photoacoustic microscopy

Brian Soetikno, Song Hu, Ernie Gonzales, Qiaonan Zhong, Konstantin Maslov, Jin Moo Lee, Lihong V. Wang

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

22 Scopus citations

Abstract

We have applied optical-resolution photoacoustic microscopy (OR-PAM) for longitudinal monitoring of cerebral metabolism through the intact skull of mice before, during, and up to 72 hours after a 1-hour transient middle cerebral artery occlusion (tMCAO). The high spatial resolution of OR-PAM enabled us to develop vessel segmentation techniques for segment-wise analysis of cerebrovascular responses.

Original languageEnglish
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2012
PublisherSPIE
ISBN (Print)9780819488664
DOIs
StatePublished - Feb 9 2012
EventPhotons Plus Ultrasound: Imaging and Sensing 2012 - San Francisco, CA, United States
Duration: Jan 22 2012Jan 24 2012

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8223
ISSN (Print)1605-7422

Conference

ConferencePhotons Plus Ultrasound: Imaging and Sensing 2012
Country/TerritoryUnited States
CitySan Francisco, CA
Period01/22/1201/24/12

Keywords

  • Ischemic stroke
  • Optical-resolution photoacoustic microscopy
  • Oxygen saturation of hemoglobin
  • Vascular anatomy
  • Vessel segmentation

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