Ventral rhizotomy enhances regeneration of uninjured sensory neurons

Keith M. Rich, Eugene M. Johnson

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Uninjured sensory neurons show metabolic and morphologic changes, as well as enhanced regeneration, when exposed to adjacent degenerating ventral root fibers. The release of a neurotrophic factor from the degenerating nerve fibers may be responsible for 'priming' the uninjured neuron and thereby enhancing its response to injury.

Original languageEnglish
Pages (from-to)182-187
Number of pages6
JournalBrain Research
Volume335
Issue number1
DOIs
StatePublished - May 27 1985

Keywords

  • axonal regeneration
  • conditioning lesion
  • nerve trauma
  • rat
  • sciatic nerve
  • ventral rhizotomy

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