TY - JOUR
T1 - Ventilation-perfusion scan
T2 - A primer for practicing radiologists
AU - Derenoncourt, Paul Robert
AU - Felder, Gabriel J.
AU - Royal, Henry D.
AU - Bhalla, Sanjeev
AU - Lang, Jordan A.
AU - Matesan, Manuela C.
AU - Itani, Malak
N1 - Funding Information:
With the COVID-19 pandemic, many institutions have shifted to perfusion-only imaging in patients with suspected PE who have suspected or documented COVID-19 infection, owing to concern about the transmissibility of COVID-19 with ventilation systems. The recommendation to forgo ventilation imaging, whenever feasible, during the pandemic is supported by guidance statements from the Society of Nuclear Medicine and Molecular Imaging (SNMMI) (11), as well as the American College of Radiology (ACR) (12).
Publisher Copyright:
© RSNA, 2021.
PY - 2021/11/1
Y1 - 2021/11/1
N2 - Lung scintigraphy, or ventilation-perfusion (V/Q) scan, is one of the commonly performed studies in nuclear medicine. Owing to vari-ability in clinical applications and different departmental workflows, many trainees are not comfortable interpreting the results of this study. This article provides a simplified overview of V/Q imaging, including a review of its technique, interpretation methods, and es-tablished and emerging clinical applications. The authors review the role of V/Q imaging in evaluation of acute and chronic pulmonary embolism, including the role of SPECT/CT and comparing V/Q scan with CT angiography. In addition, a variety of other applications of pulmonary scintigraphy are discussed, including congenital heart disease, pretreatment planning for lung cancer and emphy-sema, posttransplant imaging for bronchiolitis obliterans, and less common vascular and nonvascular pathologic conditions that may be detected with V/Q scan. This article will help radiologists and residents interpret the results of V/Q scans and understand the vari-ous potential clinical applications of this study.
AB - Lung scintigraphy, or ventilation-perfusion (V/Q) scan, is one of the commonly performed studies in nuclear medicine. Owing to vari-ability in clinical applications and different departmental workflows, many trainees are not comfortable interpreting the results of this study. This article provides a simplified overview of V/Q imaging, including a review of its technique, interpretation methods, and es-tablished and emerging clinical applications. The authors review the role of V/Q imaging in evaluation of acute and chronic pulmonary embolism, including the role of SPECT/CT and comparing V/Q scan with CT angiography. In addition, a variety of other applications of pulmonary scintigraphy are discussed, including congenital heart disease, pretreatment planning for lung cancer and emphy-sema, posttransplant imaging for bronchiolitis obliterans, and less common vascular and nonvascular pathologic conditions that may be detected with V/Q scan. This article will help radiologists and residents interpret the results of V/Q scans and understand the vari-ous potential clinical applications of this study.
UR - http://www.scopus.com/inward/record.url?scp=85120650767&partnerID=8YFLogxK
U2 - 10.1148/RG.2021210060
DO - 10.1148/RG.2021210060
M3 - Article
C2 - 34678101
AN - SCOPUS:85120650767
VL - 41
SP - 2047
EP - 2070
JO - Radiographics
JF - Radiographics
SN - 0271-5333
IS - 7
ER -