TY - JOUR
T1 - Vascular perfusion of the cochlea
T2 - Effect of potassium-free and rubidium-substituted media
AU - Wada, J.
AU - Kambayashi, J.
AU - Marcus, D. C.
AU - Thalmann, R.
PY - 1979/10
Y1 - 1979/10
N2 - By means of vascular perfusion of the cochlea with K+-free synthetic blood, it is possible to maintain the endocochlear potential (EP) at normal or supernormal levels for periods of 20-42 min. The subsequent decline of the EP is comparatively slow. This is in contrast to the immediate onset and rapid decline of the EP during perilymphatic perfusion with K+-free media. Possible implications of these data concerning the mode of generation of the EP are briefly discussed. It is further shown, that synthetic blood, in which K+ is replaced by Rb+, maintains the EP at normal or near normal levels for 2 h.
AB - By means of vascular perfusion of the cochlea with K+-free synthetic blood, it is possible to maintain the endocochlear potential (EP) at normal or supernormal levels for periods of 20-42 min. The subsequent decline of the EP is comparatively slow. This is in contrast to the immediate onset and rapid decline of the EP during perilymphatic perfusion with K+-free media. Possible implications of these data concerning the mode of generation of the EP are briefly discussed. It is further shown, that synthetic blood, in which K+ is replaced by Rb+, maintains the EP at normal or near normal levels for 2 h.
KW - Endocochlear potential
KW - K-free artificial blood
KW - Rb-substituted blood
KW - Vascular perfusion
UR - http://www.scopus.com/inward/record.url?scp=0018601650&partnerID=8YFLogxK
U2 - 10.1007/BF00455206
DO - 10.1007/BF00455206
M3 - Article
C2 - 533455
AN - SCOPUS:0018601650
SN - 0302-9530
VL - 225
SP - 79
EP - 81
JO - Archives of Oto-Rhino-Laryngology
JF - Archives of Oto-Rhino-Laryngology
IS - 2
ER -