Vascular perfusion of the cochlea: Effect of potassium-free and rubidium-substituted media

J. Wada, J. Kambayashi, D. C. Marcus, R. Thalmann

Research output: Contribution to journalArticle

56 Scopus citations

Abstract

By means of vascular perfusion of the cochlea with K+-free synthetic blood, it is possible to maintain the endocochlear potential (EP) at normal or supernormal levels for periods of 20-42 min. The subsequent decline of the EP is comparatively slow. This is in contrast to the immediate onset and rapid decline of the EP during perilymphatic perfusion with K+-free media. Possible implications of these data concerning the mode of generation of the EP are briefly discussed. It is further shown, that synthetic blood, in which K+ is replaced by Rb+, maintains the EP at normal or near normal levels for 2 h.

Original languageEnglish
Pages (from-to)79-81
Number of pages3
JournalArchives of Oto-Rhino-Laryngology
Volume225
Issue number2
DOIs
StatePublished - Oct 1 1979

Keywords

  • Endocochlear potential
  • K-free artificial blood
  • Rb-substituted blood
  • Vascular perfusion

Fingerprint Dive into the research topics of 'Vascular perfusion of the cochlea: Effect of potassium-free and rubidium-substituted media'. Together they form a unique fingerprint.

  • Cite this