Variability in Ceftriaxone Dosing across 32 US Acute Care Children's Hospitals

Rina A. Ferguson, Joshua C. Herigon, Brian R. Lee, Mari M. Nakamura, Jason G. Newland

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Ceftriaxone is one of the most common antibiotics prescribed for hospitalized children in the United States. However, ceftriaxone is not dosed consistently. Sepsis/serious bacterial infection had high dosing variability. Dosing for central nervous system infection was frequently suboptimal. Future efforts should focus on optimizing and standardizing ceftriaxone dosing.

Original languageEnglish
Pages (from-to)677-681
Number of pages5
JournalJournal of the Pediatric Infectious Diseases Society
Issue number5
StatePublished - May 1 2021


  • antibiotic dosing
  • ceftriaxone
  • inpatient antimicrobial stewardship
  • therapeutic dosing
  • weight-based dosing


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