Vanishing bile duct syndrome in a patient with advanced AIDS

Sandeep Hindupur, M. Yeung, P. Shroff, J. Fritz, N. Kirmani

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


A 39-year-old HIV-infected woman developed signs and symptoms of obstructive jaundice and cholestasis. Serological tests were positive for cytomegalovirus (CMV) infection. There was no evidence of AIDS cholangiopathy in ultrasonography or magnetic resonance cholangiopancreatography (MRCP). A liver biopsy revealed marked ductopenia and the patient was diagnosed with vanishing bile duct syndrome, thought to be secondary to CMV infection as a result of profound immunosuppression. To the best of our knowledge, this is the first reported case of vanishing bile duct syndrome diagnosed in a patient with HIV/AIDS.

Original languageEnglish
Pages (from-to)70-72
Number of pages3
JournalHIV Medicine
Issue number1
StatePublished - Jan 2007


  • Ductopenia
  • Idiopathic adulthood ductopenia
  • Intrahepatic cholestasis
  • Vanishing bile duct syndrome


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