Validation of the textural realism of a 3D anthropomorphic phantom for digital breast tomosynthesis

Raymond J. Acciavatti, Meng Kang Hsieh, Aimilia Gastounioti, Yifan Hu, Jinbo Chen, Andrew D.A. Maidment, Despina Kontos

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

4 Scopus citations

Abstract

In this paper, texture calculations are used to validate the realism of a physical anthropomorphic phantom for digital breast tomosynthesis. The texture features were compared against clinical mammography data. Three groups of features (grey-level histogram, co-occurrence, and run-length) were considered. The features were analyzed over a broad range of technique settings (kV and mAs). These calculations were done in the central slice of the reconstruction as well as the synthetic 2D mammogram. For each feature, the clinical data were binned into strata based on the compressed breast thickness. It was demonstrated that the clinical features vary by thickness. To evaluate the realism of the phantom, each feature was compared against clinical data in the same thickness stratum. For the purpose of this paper, a feature was considered to be realistic if it was within the middle 95% of the statistical distribution of clinical values. In the reconstruction, most features were found to exhibit realism; specifically, all 12 grey-level histogram features, four out of seven co-occurrence features, and three out of seven run-length features. The realism of most features was robust to changes in the technique settings. However, in the synthetic 2D mammogram, fewer features were found to exhibit realism. In conclusion, this paper provides a validation of the textural realism of the phantom in the reconstruction, and shows that there is less realism in the synthetic 2D mammogram. We identify the features that should be considered to refine the design of the phantom in future work.

Original languageEnglish
Title of host publication14th International Workshop on Breast Imaging (IWBI 2018)
EditorsElizabeth A. Krupinski
PublisherSPIE
ISBN (Electronic)9781510620070
DOIs
StatePublished - 2018
Event14th International Workshop on Breast Imaging (IWBI 2018) - Atlanta, United States
Duration: Jul 8 2018Jul 11 2018

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10718
ISSN (Print)1605-7422

Conference

Conference14th International Workshop on Breast Imaging (IWBI 2018)
Country/TerritoryUnited States
CityAtlanta
Period07/8/1807/11/18

Keywords

  • Anthropomorphic Phantom
  • Digital Breast Tomosynthesis
  • Image Acquisition
  • Image Reconstruction
  • Synthetic 2D Mammogram
  • Texture Feature Analysis

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