Validation of questionnaire information on risk factors and disease outcomes in a prospective cohort study of women

Graham A. Colditz, Pauline Martin, Meir J. Stampfer, Walter C. Willett, Laura Sampson, Bernard Rosner, Charles H. Hennekens, Frank E. Speizer

Research output: Contribution to journalArticlepeer-review

864 Scopus citations

Abstract

To assess the validity of self-reported illnesses, medical records were reviewed for participants reporting major illnesses on the biennial follow-up questionnaires used in a prospective cohort study which began in 1976. In over 90% of cases of cancer of the breast, skin, large bowel, and thyroid, histopathology reports confirmed the subjects' self-report. Lower levels of confirmation were obtained for cancers of the lung, ovary, and uterus. Application of strict diagnostic criteria also gave lower levels of confirmation for myocardial infarction (68%) and stroke (66%). Among random samples of women reporting fractures and hypertension all records obtained confirmed self-reports. For self-reported elevated cholesterol levels 85.7% of self-reports were confirmed. Self-report is a valuable epidemiologic tool but may require additional documentation when the disease is diagnostically complex.

Original languageEnglish
Pages (from-to)894-900
Number of pages7
JournalAmerican journal of epidemiology
Volume123
Issue number5
DOIs
StatePublished - May 1986

Keywords

  • Diagnosis
  • Follow-up studies
  • Medical records
  • Questionnaires

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