@article{3b2cc182d0014504bf009b9b1d4e0b3a,
title = "Validation of actigraphy for sleep measurement in children with cerebral palsy",
abstract = "Objectives: Sleep issues are common in children with cerebral palsy (CP), although there are challenges in obtaining objective data about their sleep patterns. Actigraphs measure movement to quantify sleep but their accuracy in children with CP is unknown. Our goals were to validate actigraphy for sleep assessment in children with CP and to study their sleep patterns in a cross-sectional cohort study. Methods: We recruited children with (N = 13) and without (N = 13) CP aged 2–17 years (mean age 9 y 11mo [SD 4 y 10mo] range 4–17 y; 17 males, 9 females; 54% spastic quadriplegic, 23% spastic diplegic, 15% spastic hemiplegic, 8% unclassified CP). We obtained wrist and forehead actigraphy with concurrent polysomnography for one night, and home wrist actigraphy for one week. We developed actigraphy algorithms and evaluated their accuracy (agreement with polysomnography-determined sleep versus wake staging), sensitivity (sleep detection), and specificity (wake detection). Results: Our actigraphy algorithms had median 72–80% accuracy, 87–91% sensitivity, and 60–71% specificity in children with CP and 86–89% accuracy, 88–92% sensitivity, and 70–75% specificity in children without CP, with similar accuracies in wrist and forehead locations. Our algorithms had increased specificity and accuracy compared to existing algorithms, facilitating detection of sleep disruption. Children with CP showed lower sleep efficiency and duration than children without CP. Conclusions: Actigraphy is a valid tool for sleep assessment in children with CP. Children with CP have worse sleep efficiency and duration.",
keywords = "Actigraphy, Cerebral palsy, Children, Polysomnography, Validation",
author = "Bing Xue and Amy Licis and Jill Boyd and Hoyt, {Catherine R.} and Ju, {Yo El S.}",
note = "Funding Information: This research was supported by the Washington University Institute of Clinical and Translational Sciences Pilot Award “Actigraphy Validation in Children with Spastic Quadriplegic Cerebral Palsy.” (CTSA 604; Licis, PI, NIH CTSA UL1TR002345). Research reported in this publication was supported by National Institutes of Health awards K23-NS089922 , R01-AG059507 , UL1RR024992 Sub-Award KL2-TR000450 , and the Washington University Institute of Clinical and Translational Sciences grant UL1TR000448 from the National Center for Advancing Translational Sciences (NCATS) of the National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official view of the National Institutes of Health. Funding Information: This research was supported by the Washington University Institute of Clinical and Translational Sciences Pilot Award “Actigraphy Validation in Children with Spastic Quadriplegic Cerebral Palsy.” (CTSA 604; Licis, PI, NIH CTSA UL1TR002345). Research reported in this publication was supported by National Institutes of Health awards K23-NS089922, R01-AG059507, UL1RR024992 Sub-Award KL2-TR000450, and the Washington University Institute of Clinical and Translational Sciences grant UL1TR000448 from the National Center for Advancing Translational Sciences (NCATS) of the National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official view of the National Institutes of Health. Publisher Copyright: {\textcopyright} 2022 The Authors",
year = "2022",
month = feb,
doi = "10.1016/j.sleep.2021.12.016",
language = "English",
volume = "90",
pages = "65--73",
journal = "Sleep Medicine",
issn = "1389-9457",
}