Utilization of 3-D elastic transformation in the registration of chest x-ray CT and Whole Body PET

Yuan Chuan Tai, Kang Ping Lin, Carl K. Hoh, S. C.Henry Huang, Edward J. Hoffman

Research output: Contribution to conferencePaperpeer-review

3 Scopus citations

Abstract

X-ray CT is widely used for detection and localization of lesions in the thorax. Whole Body PET with 18-FDG is becoming accepted for staging of cancer because of its ability to detect malignancy. Combining information from these two modalities has a significant value to improve lung cancer staging and treatment planning. Due to the non-rigid nature of the thorax and the differences in the acquisition conventions, the subject is stretched non-uniformly and the images of these two modalities requires non-rigid transformation for proper registration. Techniques to register chest x-ray CT and Whole Body PET images were developed and evaluated. Accuracy of 3-D elastic transformation was tested by phantom study. Studies on patients with lung carcinoma were used to validate the technique in localizing the 18-FDG uptake and in correlating PET to x-ray CT images. The fused images showed an accurate alignment and provided confident identification of the detailed anatomy of the CT with the functional information of the PET images.

Original languageEnglish
Pages1903-1907
Number of pages5
StatePublished - 1996
EventProceedings of the 1996 IEEE Nuclear Science Symposium. Part 1 (of 3) - Anaheim, CA, USA
Duration: Nov 2 1996Nov 9 1996

Conference

ConferenceProceedings of the 1996 IEEE Nuclear Science Symposium. Part 1 (of 3)
CityAnaheim, CA, USA
Period11/2/9611/9/96

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