Uterine Neoplasms, Version 3.2025 Featured Updates to the NCCN Guidelines®

Nadeem R. Abu-Rustum; Susana M. Campos; Sudha Amarnath; Rebecca Arend; Emma Barber; Kristin Bradley; Rebecca Brooks; Junzo Chino; Hye Sook Chon; Marta Ann Crispens; Shari Damast; Christine M. Fisher; Peter Frederick; David K. Gaffney; Stephanie Gaillard; Robert Giuntoli; Scott Glaser; Brooke E. Howitt; Lisa Landrum; Jayanthi Lea; Nita Lee; Gina Mantia-Smaldone; Andrea Mariani; David Mutch; Christa Nagel; Larissa Nekhlyudov; Karina Nieto; Chika Nwachukwu; Mirna Podoll; Kerry Rodabaugh; Ritu Salani; John Schorge; Scott Schuetze; Jean Siedel; Rachel Sisodia; Pamela Soliman; Stefanie Ueda; Renata Urban; Emily Wyse; Nicole McMillian; Vaishnavi Sambandam

doi:10.6004/jnccn.2025.0038

Uterine Neoplasms, Version 3.2025 Featured Updates to the NCCN Guidelines®

Nadeem R. Abu-Rustum, Susana M. Campos, Sudha Amarnath, Rebecca Arend, Emma Barber, Kristin Bradley, Rebecca Brooks, Junzo Chino, Hye Sook Chon, Marta Ann Crispens, Shari Damast, Christine M. Fisher, Peter Frederick, David K. Gaffney, Stephanie Gaillard, Robert Giuntoli, Scott Glaser, Brooke E. Howitt, Lisa Landrum, Jayanthi LeaNita Lee, Gina Mantia-Smaldone, Andrea Mariani, David Mutch, Christa Nagel, Larissa Nekhlyudov, Karina Nieto, Chika Nwachukwu, Mirna Podoll, Kerry Rodabaugh, Ritu Salani, John Schorge, Scott Schuetze, Jean Siedel, Rachel Sisodia, Pamela Soliman, Stefanie Ueda, Renata Urban, Emily Wyse, Nicole McMillian, Vaishnavi Sambandam

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4 Scopus citations

Abstract

The NCCN Guidelines for Uterine Neoplasms provide recommendations for diagnostic workup, clinical staging, and treatment options for patients with endometrial cancer and uterine sarcoma. The NCCN Cervical Uterine Panel meets at least annually to review comments from reviewers within their institutions; examine relevant new data from publications, abstracts, and recent FDA approvals; and reevaluate and update recommendations. These NCCN Guidelines Insights summarize the panel’s deliberations on the new FIGO 2023 staging system and updates on the new systemic therapy recommendations for the management of endometrial cancer.

Original language	English
Pages (from-to)	284-291
Number of pages	8
Journal	JNCCN Journal of the National Comprehensive Cancer Network
Volume	23
Issue number	8
DOIs	https://doi.org/10.6004/jnccn.2025.0038
State	Published - Aug 2025

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Abu-Rustum, N. R., Campos, S. M., Amarnath, S., Arend, R., Barber, E., Bradley, K., Brooks, R., Chino, J., Chon, H. S., Crispens, M. A., Damast, S., Fisher, C. M., Frederick, P., Gaffney, D. K., Gaillard, S., Giuntoli, R., Glaser, S., Howitt, B. E., Landrum, L., ... Sambandam, V. (2025). Uterine Neoplasms, Version 3.2025 Featured Updates to the NCCN Guidelines®. JNCCN Journal of the National Comprehensive Cancer Network, 23(8), 284-291. https://doi.org/10.6004/jnccn.2025.0038

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title = "Uterine Neoplasms, Version 3.2025 Featured Updates to the NCCN Guidelines{\textregistered}",

abstract = "The NCCN Guidelines for Uterine Neoplasms provide recommendations for diagnostic workup, clinical staging, and treatment options for patients with endometrial cancer and uterine sarcoma. The NCCN Cervical Uterine Panel meets at least annually to review comments from reviewers within their institutions; examine relevant new data from publications, abstracts, and recent FDA approvals; and reevaluate and update recommendations. These NCCN Guidelines Insights summarize the panel{\textquoteright}s deliberations on the new FIGO 2023 staging system and updates on the new systemic therapy recommendations for the management of endometrial cancer.",

author = "Abu-Rustum, \{Nadeem R.\} and Campos, \{Susana M.\} and Sudha Amarnath and Rebecca Arend and Emma Barber and Kristin Bradley and Rebecca Brooks and Junzo Chino and Chon, \{Hye Sook\} and Crispens, \{Marta Ann\} and Shari Damast and Fisher, \{Christine M.\} and Peter Frederick and Gaffney, \{David K.\} and Stephanie Gaillard and Robert Giuntoli and Scott Glaser and Howitt, \{Brooke E.\} and Lisa Landrum and Jayanthi Lea and Nita Lee and Gina Mantia-Smaldone and Andrea Mariani and David Mutch and Christa Nagel and Larissa Nekhlyudov and Karina Nieto and Chika Nwachukwu and Mirna Podoll and Kerry Rodabaugh and Ritu Salani and John Schorge and Scott Schuetze and Jean Siedel and Rachel Sisodia and Pamela Soliman and Stefanie Ueda and Renata Urban and Emily Wyse and Nicole McMillian and Vaishnavi Sambandam",

year = "2025",

month = aug,

doi = "10.6004/jnccn.2025.0038",

language = "English",

volume = "23",

pages = "284--291",

journal = "JNCCN Journal of the National Comprehensive Cancer Network",

issn = "1540-1405",

number = "8",

}

Abu-Rustum, NR, Campos, SM, Amarnath, S, Arend, R, Barber, E, Bradley, K, Brooks, R, Chino, J, Chon, HS, Crispens, MA, Damast, S, Fisher, CM, Frederick, P, Gaffney, DK, Gaillard, S, Giuntoli, R, Glaser, S, Howitt, BE, Landrum, L, Lea, J, Lee, N, Mantia-Smaldone, G, Mariani, A, Mutch, D, Nagel, C, Nekhlyudov, L, Nieto, K, Nwachukwu, C, Podoll, M, Rodabaugh, K, Salani, R, Schorge, J, Schuetze, S, Siedel, J, Sisodia, R, Soliman, P, Ueda, S, Urban, R, Wyse, E, McMillian, N & Sambandam, V 2025, 'Uterine Neoplasms, Version 3.2025 Featured Updates to the NCCN Guidelines®', JNCCN Journal of the National Comprehensive Cancer Network, vol. 23, no. 8, pp. 284-291. https://doi.org/10.6004/jnccn.2025.0038

TY - JOUR

T1 - Uterine Neoplasms, Version 3.2025 Featured Updates to the NCCN Guidelines®

AU - Abu-Rustum, Nadeem R.

AU - Campos, Susana M.

AU - Amarnath, Sudha

AU - Arend, Rebecca

AU - Barber, Emma

AU - Bradley, Kristin

AU - Brooks, Rebecca

AU - Chino, Junzo

AU - Chon, Hye Sook

AU - Crispens, Marta Ann

AU - Damast, Shari

AU - Fisher, Christine M.

AU - Frederick, Peter

AU - Gaffney, David K.

AU - Gaillard, Stephanie

AU - Giuntoli, Robert

AU - Glaser, Scott

AU - Howitt, Brooke E.

AU - Landrum, Lisa

AU - Lea, Jayanthi

AU - Lee, Nita

AU - Mantia-Smaldone, Gina

AU - Mariani, Andrea

AU - Mutch, David

AU - Nagel, Christa

AU - Nekhlyudov, Larissa

AU - Nieto, Karina

AU - Nwachukwu, Chika

AU - Podoll, Mirna

AU - Rodabaugh, Kerry

AU - Salani, Ritu

AU - Schorge, John

AU - Schuetze, Scott

AU - Siedel, Jean

AU - Sisodia, Rachel

AU - Soliman, Pamela

AU - Ueda, Stefanie

AU - Urban, Renata

AU - Wyse, Emily

AU - McMillian, Nicole

AU - Sambandam, Vaishnavi

PY - 2025/8

Y1 - 2025/8

N2 - The NCCN Guidelines for Uterine Neoplasms provide recommendations for diagnostic workup, clinical staging, and treatment options for patients with endometrial cancer and uterine sarcoma. The NCCN Cervical Uterine Panel meets at least annually to review comments from reviewers within their institutions; examine relevant new data from publications, abstracts, and recent FDA approvals; and reevaluate and update recommendations. These NCCN Guidelines Insights summarize the panel’s deliberations on the new FIGO 2023 staging system and updates on the new systemic therapy recommendations for the management of endometrial cancer.

AB - The NCCN Guidelines for Uterine Neoplasms provide recommendations for diagnostic workup, clinical staging, and treatment options for patients with endometrial cancer and uterine sarcoma. The NCCN Cervical Uterine Panel meets at least annually to review comments from reviewers within their institutions; examine relevant new data from publications, abstracts, and recent FDA approvals; and reevaluate and update recommendations. These NCCN Guidelines Insights summarize the panel’s deliberations on the new FIGO 2023 staging system and updates on the new systemic therapy recommendations for the management of endometrial cancer.

UR - https://www.scopus.com/pages/publications/105013075102

U2 - 10.6004/jnccn.2025.0038

DO - 10.6004/jnccn.2025.0038

M3 - Article

C2 - 40763788

AN - SCOPUS:105013075102

SN - 1540-1405

VL - 23

SP - 284

EP - 291

JO - JNCCN Journal of the National Comprehensive Cancer Network

JF - JNCCN Journal of the National Comprehensive Cancer Network

IS - 8

ER -

Uterine Neoplasms, Version 3.2025 Featured Updates to the NCCN Guidelines®

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