@article{c77936d0a899413a9c06708ef3ca0e3d,
title = "Using synthetic MR images for distortion correction",
abstract = "Functional MRI (fMRI) data acquired using echo-planar imaging (EPI) are highly distorted by magnetic field inhomogeneities. Distortion and differences in image contrast between EPI and T1-weighted and T2-weighted (T1w/T2w) images makes their alignment a challenge. Typically, field map data are used to correct EPI distortions. Alignments achieved with field maps can vary greatly and depends on the quality of field map data. However, many public datasets lack field map data entirely. Additionally, reliable field map data is often difficult to acquire in high-motion pediatric or developmental cohorts. To address this, we developed Synth, a software package for distortion correction and cross-modal image registration that does not require field map data. Synth combines information from T1w and T2w anatomical images to construct an idealized undistorted synthetic image with similar contrast properties to EPI data. This synthetic image acts as an effective reference for individual-specific distortion correction. Using pediatric (ABCD: Adolescent Brain Cognitive Development) and adult (MSC: Midnight Scan Club; HCP: Human Connectome Project) data, we demonstrate that Synth performs comparably to field map distortion correction approaches, and often outperforms them. Field map-less distortion correction with Synth allows accurate and precise registration of fMRI data with missing or corrupted field map information.",
keywords = "Distortion correction, EPI, Field map, Registration, fMRI",
author = "Montez, {David F.} and Van, {Andrew N.} and Miller, {Ryland L.} and Seider, {Nicole A.} and Scott Marek and Annie Zheng and Newbold, {Dillan J.} and Kristen Scheidter and Eric Feczko and Perrone, {Anders J.} and Oscar Miranda-Dominguez and Earl, {Eric A.} and Kay, {Benjamin P.} and Jha, {Abhinav K.} and Aristeidis Sotiras and Laumann, {Timothy O.} and Greene, {Deanna J.} and Gordon, {Evan M.} and Tisdall, {M. Dylan} and {van der Kouwe}, Andre and Fair, {Damien A.} and Dosenbach, {Nico U.F.}",
note = "Funding Information: This work was supported by DA007261 (D.F.M.), MH096773 (D.A.F, N.U.F.D.), MH122066 (D.A.F. N.U.F.D.), MH121276 (D.A.F. N.U.F.D), MH124567 (D.A.F. N.U.F.D.), MH100019 (T.O.L.), NS110332 (D.J.N. N.U.F.D.), NS088590 (N.U.F.D.), Kiwanis Neuroscience Research Foundation (N.U.F.D.), the Jacobs Foundation, Germany grant 2016121703 (N.U.F.D.). Data used in the preparation of this article were obtained from the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org), held in the NIMH Data Archive (NDA). This is a multisite, longitudinal study designed to recruit more than 10,000 children age 9–10 and follow them over 10 years into early adulthood. The ABCD Study is supported by the National Institutes of Health and additional federal partners under award numbers U01DA041022, U01DA041028, U01DA041048, U01DA041089, U01DA041106,U01DA041117, U01DA041120, U01DA041134, U01DA041148, U01DA041156, U01DA041174, U24DA041123, U24DA041147, U01DA041093, and U01DA041025. A full list of supporters is available at https://abcdstudy.org/federal-partners.html. A listing of participating sites and a complete listing of the study investigators can be found at https://abcdstudy.org/scientists/workgroups/. ABCD consortium investigators designed and implemented the study and/or provided data but did not necessarily participate in analysis or writing of this report. This manuscript reflects the views of the authors and may not reflect the opinions or views of the NIH or ABCD consortium investigators. Data were provided [in part] by the Human Connectome Project, WU-Minn Consortium (Principal Investigators: David Van Essen and Kamil Ugurbil; 1U54MH091657) funded by the 16 NIH Institutes and Centers that support the NIH Blueprint for Neuroscience Research; and by the McDonnell Center for Systems Neuroscience at Washington University. Funding Information: This work was supported by DA007261 (D.F.M.), MH096773 (D.A.F, N.U.F.D.), MH122066 (D.A.F., N.U.F.D.), MH121276 (D.A.F., N.U.F.D), MH124567 (D.A.F., N.U.F.D.), MH100019 (T.O.L.), NS110332 (D.J.N., N.U.F.D.), NS088590 (N.U.F.D.), Kiwanis Neuroscience Research Foundation (N.U.F.D.), the Jacobs Foundation, Germany grant 2016121703 (N.U.F.D.). Funding Information: Data were provided [in part] by the Human Connectome Project, WU-Minn Consortium (Principal Investigators: David Van Essen and Kamil Ugurbil; 1U54MH091657) funded by the 16 NIH Institutes and Centers that support the NIH Blueprint for Neuroscience Research; and by the McDonnell Center for Systems Neuroscience at Washington University. Funding Information: Data used in the preparation of this article were obtained from the Adolescent Brain Cognitive Development (ABCD) Study ( https://abcdstudy.org ), held in the NIMH Data Archive (NDA). This is a multisite, longitudinal study designed to recruit more than 10,000 children age 9–10 and follow them over 10 years into early adulthood. The ABCD Study is supported by the National Institutes of Health and additional federal partners under award numbers U01DA041022, U01DA041028, U01DA041048, U01DA041089, U01DA041106,U01DA041117, U01DA041120, U01DA041134, U01DA041148, U01DA041156, U01DA041174, U24DA041123, U24DA041147, U01DA041093, and U01DA041025. A full list of supporters is available at https://abcdstudy.org/federal-partners.html . A listing of participating sites and a complete listing of the study investigators can be found at https://abcdstudy.org/scientists/workgroups/ . ABCD consortium investigators designed and implemented the study and/or provided data but did not necessarily participate in analysis or writing of this report. This manuscript reflects the views of the authors and may not reflect the opinions or views of the NIH or ABCD consortium investigators. Publisher Copyright: {\textcopyright} 2023 The Author(s)",
year = "2023",
month = apr,
doi = "10.1016/j.dcn.2023.101234",
language = "English",
volume = "60",
journal = "Developmental Cognitive Neuroscience",
issn = "1878-9293",
}