Using Caveolin-1 Knockout Mouse to Study Impaired Detrusor Contractility and Disrupted Muscarinic Activity in the Aging Bladder

Keyphrases

• Knock-in Mouse Model 100%
• Caveolin-1 (Cav-1) 100%
• Aging Bladder 100%
• Impaired Detrusor Contractility 100%
• 1-year-olds 66%
• Bladder 50%
• Bladder Strips 50%
• Wild Mice 33%
• Potassium 33%
• Receptor Agonist 33%
• Adenosine Triphosphate 33%
• Contractility 33%
• Methylene 33%
• Carbachol 33%
• Age-matched 16%
• Old Age 16%
• Aging Effect 16%
• Young Males 16%
• Detrusor Overactivity 16%
• Knockout Animals 16%
• Littermate Controls 16%
• Cholinergic Receptors 16%
• Purinergic Receptors 16%
• Bladder Contractility 16%
• Cholinergic Pathway 16%
• Evoked Contractions 16%
• Depolarizing Agents 16%
• Detrusor Contractility 16%

Medicine and Dentistry

• Bladder 100%
• Muscle Contractility 100%
• Caveolin 1 100%
• Detrusor 100%
• Adenosine Triphosphate 22%
• Carbene 22%
• Carbachol 22%
• Overactive Bladder 11%
• Isometrics 11%
• Parasympathomimetic Drug 11%
• Purinergic Receptor Stimulating Agent 11%

Pharmacology, Toxicology and Pharmaceutical Science

• Knockout Mouse 100%
• Caveolin 1 100%
• Cholinergic Receptor Stimulating Agent 50%
• Wild Type Mouse 33%
• Adenosine Triphosphate 33%
• Isotopes of Potassium 33%
• Carbachol 33%
• Carbene 33%
• Overactive Bladder 16%
• Purinergic Receptor Stimulating Agent 16%