Usefulness of echocardiographic tissue synchronization imaging to predict acute response to cardiac resynchronization therapy

John Gorcsan, Hideaki Kanzaki, Raveen Bazaz, Kaoru Dohi, David Schwartzman

Research output: Contribution to journalArticlepeer-review

244 Scopus citations

Abstract

Echocardiographic tissue synchronization imaging (TSI) consists of color-coding time-to-peak tissue Doppler velocities. This study of 29 patients who underwent cardiac resynchronization therapy (CRT) demonstrated that differences in baseline time-to-speak velocities of opposing ventricular walls by TSI were greater in 15 patients, with an acute hemodynamic improvement. A ≥65 ms delay from the anterior septum to the posterior wall using the apical long-axis view had 87% sensitivity and 100% specificity for predicting an acute response. Although a subgroup without acute improvement had later decreases in end-systolic volume, suggesting that acute response underestimates long-term effects, TSI has potential to assist in guiding CRT.

Original languageEnglish
Pages (from-to)1178-1181
Number of pages4
JournalAmerican Journal of Cardiology
Volume93
Issue number9
DOIs
StatePublished - May 1 2004
Externally publishedYes

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