TY - JOUR
T1 - Usefulness of echocardiographic tissue synchronization imaging to predict acute response to cardiac resynchronization therapy
AU - Gorcsan, John
AU - Kanzaki, Hideaki
AU - Bazaz, Raveen
AU - Dohi, Kaoru
AU - Schwartzman, David
N1 - Funding Information:
Dr. Gorcsan was supported in part by award K24 HL04503-01 from the National Institutes of Health, Bethesda, Maryland and the National grant-in-aid 0050587N from the American Heart Association, Dallas, Texas.
PY - 2004/5/1
Y1 - 2004/5/1
N2 - Echocardiographic tissue synchronization imaging (TSI) consists of color-coding time-to-peak tissue Doppler velocities. This study of 29 patients who underwent cardiac resynchronization therapy (CRT) demonstrated that differences in baseline time-to-speak velocities of opposing ventricular walls by TSI were greater in 15 patients, with an acute hemodynamic improvement. A ≥65 ms delay from the anterior septum to the posterior wall using the apical long-axis view had 87% sensitivity and 100% specificity for predicting an acute response. Although a subgroup without acute improvement had later decreases in end-systolic volume, suggesting that acute response underestimates long-term effects, TSI has potential to assist in guiding CRT.
AB - Echocardiographic tissue synchronization imaging (TSI) consists of color-coding time-to-peak tissue Doppler velocities. This study of 29 patients who underwent cardiac resynchronization therapy (CRT) demonstrated that differences in baseline time-to-speak velocities of opposing ventricular walls by TSI were greater in 15 patients, with an acute hemodynamic improvement. A ≥65 ms delay from the anterior septum to the posterior wall using the apical long-axis view had 87% sensitivity and 100% specificity for predicting an acute response. Although a subgroup without acute improvement had later decreases in end-systolic volume, suggesting that acute response underestimates long-term effects, TSI has potential to assist in guiding CRT.
UR - http://www.scopus.com/inward/record.url?scp=1942467990&partnerID=8YFLogxK
U2 - 10.1016/j.amjcard.2004.01.054
DO - 10.1016/j.amjcard.2004.01.054
M3 - Article
C2 - 15110219
AN - SCOPUS:1942467990
VL - 93
SP - 1178
EP - 1181
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
IS - 9
ER -