TY - JOUR
T1 - Use of the rabbit larynx in an excised larynx setup
AU - Maytag, Allison L.
AU - Robitaille, Mark J.
AU - Rieves, Adam L.
AU - Madsen, James
AU - Smith, Benjamin L.
AU - Jiang, Jack J.
N1 - Funding Information:
The authors would like to thank Henry Tsui and Ketan Surender for designing the programs used for videokymographic and electroglottographic data analysis. This study was funded by National Institutes of Health grant numbers R01 DC008153 , R01 DC05522 , and R01 DC008850 from the National Institute on Deafness and other Communicative Disorders .
PY - 2013/1
Y1 - 2013/1
N2 - Objective: To modify the excised larynx bench apparatus to accommodate experiments with rabbit larynges. Study Design: Methodological study using ex vivo rabbit larynges. Methods: Rabbit larynges (n = 5) were dissected and mounted on a custom-made phonatory apparatus. The arytenoids were adducted by rods, and humidified air was passed through the larynx to elicit vocal fold vibration. Acoustic, aerodynamic, electroglottographic (EGG), and videokymographic data were collected for each larynx. The same data were collected for five canine larynges for the purpose of comparison, and coefficients of variation were calculated for each parameter in both models. Results: Reliable phonation was achieved in each larynx. Acoustic fundamental frequency (F0), percent jitter, percent shimmer, signal-to-noise ratio, pressure and flow at phonation onset and offset; and F0, closed quotient, speed quotient, jitter, shimmer, and contact quotient, as recorded by EGG; and mucosal wave amplitude and phase difference are reported for rabbit larynges. Coefficients of variation for each parameter are similar in magnitude between the two models. Conclusion: We developed a method for recording reliable acoustic, aerodynamic, videokymographic, and EGG data from rabbit larynges. When data obtained from leporine larynges were compared with data from canine larynges, the intralarynx variability of rabbit larynges was found to be similar to that of canine larynges.
AB - Objective: To modify the excised larynx bench apparatus to accommodate experiments with rabbit larynges. Study Design: Methodological study using ex vivo rabbit larynges. Methods: Rabbit larynges (n = 5) were dissected and mounted on a custom-made phonatory apparatus. The arytenoids were adducted by rods, and humidified air was passed through the larynx to elicit vocal fold vibration. Acoustic, aerodynamic, electroglottographic (EGG), and videokymographic data were collected for each larynx. The same data were collected for five canine larynges for the purpose of comparison, and coefficients of variation were calculated for each parameter in both models. Results: Reliable phonation was achieved in each larynx. Acoustic fundamental frequency (F0), percent jitter, percent shimmer, signal-to-noise ratio, pressure and flow at phonation onset and offset; and F0, closed quotient, speed quotient, jitter, shimmer, and contact quotient, as recorded by EGG; and mucosal wave amplitude and phase difference are reported for rabbit larynges. Coefficients of variation for each parameter are similar in magnitude between the two models. Conclusion: We developed a method for recording reliable acoustic, aerodynamic, videokymographic, and EGG data from rabbit larynges. When data obtained from leporine larynges were compared with data from canine larynges, the intralarynx variability of rabbit larynges was found to be similar to that of canine larynges.
KW - Excised larynx
KW - Phonation
KW - Rabbit larynx
UR - http://www.scopus.com/inward/record.url?scp=84872008048&partnerID=8YFLogxK
U2 - 10.1016/j.jvoice.2012.08.004
DO - 10.1016/j.jvoice.2012.08.004
M3 - Article
C2 - 23159025
AN - SCOPUS:84872008048
SN - 0892-1997
VL - 27
SP - 24
EP - 28
JO - Journal of Voice
JF - Journal of Voice
IS - 1
ER -