TY - JOUR
T1 - Use of the 'perceptron' algorithm to distinguish translational initiation sites in E. coli
AU - Stormo, Gary D.
AU - Schneider, Thomas D.
AU - Gold, Larry
AU - Ehrenfeucht, Andrzej
N1 - Publisher Copyright:
© 1982 IRL Press Limited.
PY - 1982/5/11
Y1 - 1982/5/11
N2 - We have used a "Perceptron" algorithm to find a weighting function which distinguishes E. coli translational initiation sites from all other sites in a library of over 78,000 nucleotides of mRNA sequence. The "Perceptron" examined sequences as linear representations. The "Perceptron" is more successful at finding gene beginnings than our previous searches using "rules" (see previous paper). We note that the weighting function can find translational initiation sites within sequences that were not included in the training set.
AB - We have used a "Perceptron" algorithm to find a weighting function which distinguishes E. coli translational initiation sites from all other sites in a library of over 78,000 nucleotides of mRNA sequence. The "Perceptron" examined sequences as linear representations. The "Perceptron" is more successful at finding gene beginnings than our previous searches using "rules" (see previous paper). We note that the weighting function can find translational initiation sites within sequences that were not included in the training set.
UR - http://www.scopus.com/inward/record.url?scp=0020480251&partnerID=8YFLogxK
U2 - 10.1093/nar/10.9.2997
DO - 10.1093/nar/10.9.2997
M3 - Article
C2 - 7048259
AN - SCOPUS:0020480251
SN - 0305-1048
VL - 10
SP - 2997
EP - 3011
JO - Nucleic acids research
JF - Nucleic acids research
IS - 9
ER -