Use of 18F-PSMA PET to Distinguish Cerebral Radiation Necrosis From Tumor Recurrence

Sampanna Jung Rayamajhi, Maria Rosana Ponisio, Barry Siegel

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Brain metastasis in prostate adenocarcinoma is extremely rare and usually arises in the setting of widespread osseous and visceral metastases. Surgical resection and radiation therapy, including stereotactic radiosurgery, are the mainstays of treatment for brain metastasis. Radiation necrosis is a common complication of radiotherapy for brain metastasis, and distinguishing it from tumor recurrence by MRI is difficult because of overlapping findings. We present a 73-year-old man with prostate cancer with a solitary brain metastasis where PET with 18F-piflufolostat helped detect disease recurrence in the setting of ambiguous MRI findings.

Original languageEnglish
Pages (from-to)E483-E484
JournalClinical nuclear medicine
Volume48
Issue number10
DOIs
StatePublished - Oct 1 2023

Keywords

  • F-piflufolostat
  • PSMA
  • radiation necrosis

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