TY - JOUR
T1 - Use of 18F-PSMA PET to Distinguish Cerebral Radiation Necrosis From Tumor Recurrence
AU - Rayamajhi, Sampanna Jung
AU - Ponisio, Maria Rosana
AU - Siegel, Barry
N1 - Publisher Copyright:
© Wolters Kluwer Health, Inc. All rights reserved.
PY - 2023/10/1
Y1 - 2023/10/1
N2 - Brain metastasis in prostate adenocarcinoma is extremely rare and usually arises in the setting of widespread osseous and visceral metastases. Surgical resection and radiation therapy, including stereotactic radiosurgery, are the mainstays of treatment for brain metastasis. Radiation necrosis is a common complication of radiotherapy for brain metastasis, and distinguishing it from tumor recurrence by MRI is difficult because of overlapping findings. We present a 73-year-old man with prostate cancer with a solitary brain metastasis where PET with 18F-piflufolostat helped detect disease recurrence in the setting of ambiguous MRI findings.
AB - Brain metastasis in prostate adenocarcinoma is extremely rare and usually arises in the setting of widespread osseous and visceral metastases. Surgical resection and radiation therapy, including stereotactic radiosurgery, are the mainstays of treatment for brain metastasis. Radiation necrosis is a common complication of radiotherapy for brain metastasis, and distinguishing it from tumor recurrence by MRI is difficult because of overlapping findings. We present a 73-year-old man with prostate cancer with a solitary brain metastasis where PET with 18F-piflufolostat helped detect disease recurrence in the setting of ambiguous MRI findings.
KW - F-piflufolostat
KW - PSMA
KW - radiation necrosis
UR - http://www.scopus.com/inward/record.url?scp=85170295227&partnerID=8YFLogxK
U2 - 10.1097/RLU.0000000000004785
DO - 10.1097/RLU.0000000000004785
M3 - Article
C2 - 37486317
AN - SCOPUS:85170295227
SN - 0363-9762
VL - 48
SP - E483-E484
JO - Clinical nuclear medicine
JF - Clinical nuclear medicine
IS - 10
ER -