TY - JOUR
T1 - Use of stable isotopically labeled tracers for studies of metabolic kinetics
T2 - An overview
AU - Patterson, Bruce W.
N1 - Funding Information:
From the Departmem of Internal Medicine. Washington University School of Medicine, St Louis. MO. Submitted September 19. 1996: accepted September 23. 1996. Supported b~ National Institutes of Health Grant No. CA62177. Presented at the National Institutes of Health Symposium, "In Vivo Tracer Kinetics and Modeling; "" May 3. 1996, National Institutes of Health. Bethesda. MD. Address reprint requests to Bruce W Patterson PhD. Department oJ Internal Medicine. Washington University School of Medicine. 660 S EuclidAve. Box 8127. St Louis. MO 63110. Copyright © 1997 by WB. Saunders Company 0026-0495/97/4603-0015503.00/0
PY - 1997
Y1 - 1997
N2 - Stable isotopically labeled tracers offer a reliable and safe alternative to the use of radioactive tracers for studies of metabolic kinetics. This overview examines some of the principles and technical issues regarding mass spectrometry instrumentation, and reviews some of the approaches used in the application of stable isotopically labeled tracers to studies of protein, lipid, and carbohydrate metabolic kinetics.
AB - Stable isotopically labeled tracers offer a reliable and safe alternative to the use of radioactive tracers for studies of metabolic kinetics. This overview examines some of the principles and technical issues regarding mass spectrometry instrumentation, and reviews some of the approaches used in the application of stable isotopically labeled tracers to studies of protein, lipid, and carbohydrate metabolic kinetics.
UR - http://www.scopus.com/inward/record.url?scp=0031034862&partnerID=8YFLogxK
U2 - 10.1016/S0026-0495(97)90260-2
DO - 10.1016/S0026-0495(97)90260-2
M3 - Article
C2 - 9054476
AN - SCOPUS:0031034862
SN - 0026-0495
VL - 46
SP - 322
EP - 329
JO - Metabolism: clinical and experimental
JF - Metabolism: clinical and experimental
IS - 3
ER -