Use of intravenous acyclovir for treatment of herpes zoster ophthalmicus in patients at risk for AIDS.

S. R. Seiff, T. Margolis, S. H. Graham, J. J. O'Donnell

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Patients who are homosexual, intravenous drug abusers, or have received multiple blood transfusions are at greater risk to contract the immunosuppressive disorders of acquired immunodeficiency syndrome (AIDS) and AIDS-related complex (ARC). These persons also have a greater chance of developing serious neurologic complications after an episode of Herpes zoster. We present two cases which emphasize the serious complications of Herpes zoster ophthalmicus in such patients. Since systemically administered acyclovir may shorten the disease course and reduce the complications of Herpes zoster in immunocompromised individuals, the authors favor treatment of all such patients who have Herpes zoster ophthalmicus with a seven-day course of high-dose (30 mg/kg/day) intravenous acyclovir. To minimize serious neurologic complications in such patients, treatment should be instituted immediately before the results of human immunodeficiency virus (HIV) testing are known.

Original languageEnglish
Pages (from-to)480-482
Number of pages3
JournalAnnals of ophthalmology
Volume20
Issue number12
StatePublished - Dec 1 1988
Externally publishedYes

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