Use of Concomitant Antibiotics During Treatment for Clostridium difficile Infection (CDI) in Pediatric Inpatients: An Observational Cohort Study

Vanessa W. Stevens; Cary Thurm; Elyse M. Schwab; Matthew P. Kronman; Jeffrey S. Gerber; Samir S. Shah; Jason G. Newland; Joshua Courter; Sarah Parker; Thomas V. Brogan; Adam L. Hersh

doi:10.1007/s40121-016-0105-2

Use of Concomitant Antibiotics During Treatment for Clostridium difficile Infection (CDI) in Pediatric Inpatients: An Observational Cohort Study

Vanessa W. Stevens
, Cary Thurm
, Elyse M. Schwab
, Matthew P. Kronman
, Jeffrey S. Gerber
, Samir S. Shah
, Jason G. Newland
, Joshua Courter
, Sarah Parker
, Thomas V. Brogan
, Adam L. Hersh

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Concomitant antibiotic use during treatment for Clostridium difficile infection (CDI) increases the risk of recurrence. Across a network of children’s hospitals, 46% of patients treated for CDI received concomitant antibiotics for a median of 7 days. Concomitant antibiotic use was more common among patients with malignancies, and solid organ or bone marrow transplant. Unnecessary concomitant antibiotic use in CDI patients is a potential target for pediatric antimicrobial stewardship.

Original language	English
Pages (from-to)	45-51
Number of pages	7
Journal	Infectious Diseases and Therapy
Volume	5
Issue number	1
DOIs	https://doi.org/10.1007/s40121-016-0105-2
State	Published - Mar 1 2016

Keywords

Clostridium difficile infection
Concomitant antibiotics
Pediatric

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10.1007/s40121-016-0105-2

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Stevens, V. W., Thurm, C., Schwab, E. M., Kronman, M. P., Gerber, J. S., Shah, S. S., Newland, J. G., Courter, J., Parker, S., Brogan, T. V., & Hersh, A. L. (2016). Use of Concomitant Antibiotics During Treatment for Clostridium difficile Infection (CDI) in Pediatric Inpatients: An Observational Cohort Study. Infectious Diseases and Therapy, 5(1), 45-51. https://doi.org/10.1007/s40121-016-0105-2

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title = "Use of Concomitant Antibiotics During Treatment for Clostridium difficile Infection (CDI) in Pediatric Inpatients: An Observational Cohort Study",

abstract = "Concomitant antibiotic use during treatment for Clostridium difficile infection (CDI) increases the risk of recurrence. Across a network of children{\textquoteright}s hospitals, 46\% of patients treated for CDI received concomitant antibiotics for a median of 7 days. Concomitant antibiotic use was more common among patients with malignancies, and solid organ or bone marrow transplant. Unnecessary concomitant antibiotic use in CDI patients is a potential target for pediatric antimicrobial stewardship.",

keywords = "Clostridium difficile infection, Concomitant antibiotics, Pediatric",

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note = "Publisher Copyright: {\textcopyright} 2016, The Author(s).",

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doi = "10.1007/s40121-016-0105-2",

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Stevens, VW, Thurm, C, Schwab, EM, Kronman, MP, Gerber, JS, Shah, SS, Newland, JG, Courter, J, Parker, S, Brogan, TV & Hersh, AL 2016, 'Use of Concomitant Antibiotics During Treatment for Clostridium difficile Infection (CDI) in Pediatric Inpatients: An Observational Cohort Study', Infectious Diseases and Therapy, vol. 5, no. 1, pp. 45-51. https://doi.org/10.1007/s40121-016-0105-2

TY - JOUR

T1 - Use of Concomitant Antibiotics During Treatment for Clostridium difficile Infection (CDI) in Pediatric Inpatients

T2 - An Observational Cohort Study

AU - Stevens, Vanessa W.

AU - Thurm, Cary

AU - Schwab, Elyse M.

AU - Kronman, Matthew P.

AU - Gerber, Jeffrey S.

AU - Shah, Samir S.

AU - Newland, Jason G.

AU - Courter, Joshua

AU - Parker, Sarah

AU - Brogan, Thomas V.

AU - Hersh, Adam L.

PY - 2016/3/1

Y1 - 2016/3/1

N2 - Concomitant antibiotic use during treatment for Clostridium difficile infection (CDI) increases the risk of recurrence. Across a network of children’s hospitals, 46% of patients treated for CDI received concomitant antibiotics for a median of 7 days. Concomitant antibiotic use was more common among patients with malignancies, and solid organ or bone marrow transplant. Unnecessary concomitant antibiotic use in CDI patients is a potential target for pediatric antimicrobial stewardship.

AB - Concomitant antibiotic use during treatment for Clostridium difficile infection (CDI) increases the risk of recurrence. Across a network of children’s hospitals, 46% of patients treated for CDI received concomitant antibiotics for a median of 7 days. Concomitant antibiotic use was more common among patients with malignancies, and solid organ or bone marrow transplant. Unnecessary concomitant antibiotic use in CDI patients is a potential target for pediatric antimicrobial stewardship.

KW - Clostridium difficile infection

KW - Concomitant antibiotics

KW - Pediatric

UR - https://www.scopus.com/pages/publications/84977151010

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DO - 10.1007/s40121-016-0105-2

M3 - Article

AN - SCOPUS:84977151010

SN - 2193-8229

VL - 5

SP - 45

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JO - Infectious Diseases and Therapy

JF - Infectious Diseases and Therapy

IS - 1

ER -

Use of Concomitant Antibiotics During Treatment for Clostridium difficile Infection (CDI) in Pediatric Inpatients: An Observational Cohort Study

Abstract

Keywords

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