Use of Concomitant Antibiotics During Treatment for Clostridium difficile Infection (CDI) in Pediatric Inpatients: An Observational Cohort Study

Vanessa W. Stevens, Cary Thurm, Elyse M. Schwab, Matthew P. Kronman, Jeffrey S. Gerber, Samir S. Shah, Jason G. Newland, Joshua Courter, Sarah Parker, Thomas V. Brogan, Adam L. Hersh

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Concomitant antibiotic use during treatment for Clostridium difficile infection (CDI) increases the risk of recurrence. Across a network of children’s hospitals, 46% of patients treated for CDI received concomitant antibiotics for a median of 7 days. Concomitant antibiotic use was more common among patients with malignancies, and solid organ or bone marrow transplant. Unnecessary concomitant antibiotic use in CDI patients is a potential target for pediatric antimicrobial stewardship.

Original languageEnglish
Pages (from-to)45-51
Number of pages7
JournalInfectious Diseases and Therapy
Volume5
Issue number1
DOIs
StatePublished - Mar 1 2016

Keywords

  • Clostridium difficile infection
  • Concomitant antibiotics
  • Pediatric

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