@inbook{43a3f205c74b4c959eca446d48f6de82,
title = "Use of cationized ferritin nanoparticles to measure renal glomerular microstructure with MRI",
abstract = "Magnetic resonance imaging (MRI) is becoming important for whole-kidney assessment of glomerular morphology, both in vivo and ex vivo. MRI-based renal morphological measurements can be made in intact organs and allow direct measurements of every perfused glomerulus. Cationic ferritin (CF) is used as a superparamagnetic contrast agent for MRI. CF binds to the glomerular basement membrane after intravenous injection, allowing direct, whole-kidney measurements of glomerular number, volume, and volume distribution. Here we describe the production, testing, and use of CF as an MRI contrast agent for quantitative glomerular morphology in intact mouse, rat, and human kidneys.",
keywords = "Cationic ferritin, Chronic kidney disease, Contrast agent, Glomerulus, Kidney, Magnetic resonance imaging, Morphology",
author = "Bennett, {Kevin M.} and Beeman, {Scott C.} and Baldelomar, {Edwin J.} and Min Zhang and Teresa Wu and Hann, {Bradley D.} and Bertram, {John F.} and Charlton, {Jennifer R.}",
note = "Publisher Copyright: {\textcopyright} Springer Science+Business Media New York 2016.",
year = "2016",
doi = "10.1007/978-1-4939-3353-2_7",
language = "English",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "67--79",
booktitle = "Methods in Molecular Biology",
}