Abstract
Summary: We evaluated a recombinant antigen (OC 3.6 cDNA) expressed in pMAL TM vector for the diagnosis of onchocerciasis in children living in an endemic focus of forest-type onchocerciasis in Nigeria. Using the Western blot with the maltose-binding fusion protein as antigen, 91 per cent of mf-positive children and 24 per cent of endemic normal children were positive. Furthermore, age was not a limitation to the assay. The practical limitations of the assay for field diagnosis of onchocerciasis is discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 103-105 |
| Number of pages | 3 |
| Journal | Journal of Tropical Pediatrics |
| Volume | 38 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jun 1 1992 |
Fingerprint Dive into the research topics of 'Use of a recombinant antigen (OC 3.6 cDNA) for the serological diagnosis of onchocerciasis in exposed Nigerian children'. Together they form a unique fingerprint.
Cite this
Ogunrinade, A. F., Chandrashekar, R., Weil, G. J., & Kale, O. O. (1992). Use of a recombinant antigen (OC 3.6 cDNA) for the serological diagnosis of onchocerciasis in exposed Nigerian children. Journal of Tropical Pediatrics, 38(3), 103-105. https://doi.org/10.1093/tropej/38.3.103