UPEC hemolysin: More than just for making holes

Sheryl S. Justice, David A. Hunstad

Research output: Contribution to journalShort surveypeer-review

13 Scopus citations

Abstract

During acute cystitis, uropathogenic Escherichia coli (UPEC) induce bladder epithelial cell exfoliation, which eliminates infected cells and promotes UPEC dissemination. Dhakal and Mulvey (2012) uncover the mechanism that induces this exfoliation and reintroduce the pore-forming toxin, hemolysin, as an effector that surprisingly targets multiple host pathways to facilitate infection.

Original languageEnglish
Pages (from-to)4-5
Number of pages2
JournalCell Host and Microbe
Volume11
Issue number1
DOIs
StatePublished - Jan 19 2012

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