TY - JOUR
T1 - Update in the management of acne in adolescence
AU - Mwanthi, Muithi
AU - Zaenglein, Andrea L.
N1 - Publisher Copyright:
© 2018 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2018/8/1
Y1 - 2018/8/1
N2 - Purpose of reviewThis review will update the pediatric provider on recent data on the pathogenesis and treatment of acne in adolescent patients. A special focus was made to summarize recent guidelines and fill in several identified practice gaps.Recent findingsOur understanding of the pathogenesis of acne is greatly expanding and data is emerging to tie diet, particularly the role of IGF-1 with inflammation in acne. Additionally, stronger recommendations to limit antibiotic usage in acne are being made worldwide. Although retinoids are considered the base of most effective acne treatment strategies, data suggests that all providers need to emphasize their importance in maintenance of acne.SummaryAn effective acne management strategy targets multiple pathogenic factors in acne, using a retinoid as the foundation. Systemic antibiotics for moderate-to-severe acne should be used for acute management, then discontinued at 3-4 months, while maintaining on topical treatments. If therapy is ineffective, alternate treatments, such as combined oral contraceptives in females or isotretinoin, should be promptly employed to prevent prolonged psychological impact and cutaneous scarring.
AB - Purpose of reviewThis review will update the pediatric provider on recent data on the pathogenesis and treatment of acne in adolescent patients. A special focus was made to summarize recent guidelines and fill in several identified practice gaps.Recent findingsOur understanding of the pathogenesis of acne is greatly expanding and data is emerging to tie diet, particularly the role of IGF-1 with inflammation in acne. Additionally, stronger recommendations to limit antibiotic usage in acne are being made worldwide. Although retinoids are considered the base of most effective acne treatment strategies, data suggests that all providers need to emphasize their importance in maintenance of acne.SummaryAn effective acne management strategy targets multiple pathogenic factors in acne, using a retinoid as the foundation. Systemic antibiotics for moderate-to-severe acne should be used for acute management, then discontinued at 3-4 months, while maintaining on topical treatments. If therapy is ineffective, alternate treatments, such as combined oral contraceptives in females or isotretinoin, should be promptly employed to prevent prolonged psychological impact and cutaneous scarring.
KW - acne vulgaris
KW - benzoyl peroxide
KW - dapsone
KW - hormonal therapies
KW - retinoids
KW - tetracyclines
UR - http://www.scopus.com/inward/record.url?scp=85061581818&partnerID=8YFLogxK
U2 - 10.1097/MOP.0000000000000649
DO - 10.1097/MOP.0000000000000649
M3 - Review article
C2 - 29846254
AN - SCOPUS:85061581818
SN - 1040-8703
VL - 30
SP - 492
EP - 498
JO - Current opinion in pediatrics
JF - Current opinion in pediatrics
IS - 4
ER -