Untreated lung cancer: Quantification of systematic distortion of tumor size and shape on non-attenuation-corrected 2-[fluorine-18]fluoro-2-deoxy-D- glucose PET scans

Kenneth R. Zasadny, Paul V. Kison, Leslie E. Quint, Richard L. Wahl

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

The authors quantitatively evaluated possible distortions of tumor size and shape introduced on non-attenuation-corrected 2-[fluorine-18] fluoro-2- deoxy-D-glucose (FDG) positron emission tomography (PET) scans obtained in primary lung cancer tumors. Primary lung cancer tumors in 21 patients were measured on x-ray computed tomography (CT), attenuation-corrected FDG PET, and non-attenuation-corrected FDG PET scans. Apparent anteroposterior tumor dimensions on non-attenuation-corrected FDG PET scans were significantly larger (P = .0007; mean difference, 30%) than on attenuation-corrected FDG PET or CT scans (P = .05; mean difference, 28%). Left-to-right tumor dimensions on non-attenuation-corrected FDG PET scans were significantly smaller than on attenuation-corrected FDG PET scans (P = .03; mean difference, 8.5%) but were not significantly different from those on CT scans (P = .3).

Original languageEnglish
Pages (from-to)873-876
Number of pages4
JournalRadiology
Volume201
Issue number3
DOIs
StatePublished - Dec 1996
Externally publishedYes

Keywords

  • Compared tomography (CT), comparative studies
  • Emission CT (ECT)
  • Lung neoplasms, CT
  • Lung neoplasms, emission CT Lung neoplasms, staging
  • comparative studies

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